DOI QR코드

DOI QR Code

Highly Sensitive Fluorescent Probes for the Quantitative Determination of Singlet Oxygen (1O2)

  • Ahmed, Syed Rahin (Department of Nanofusion Technology, College of Nanoscience and Nanotechnology, Pusan National University) ;
  • Koh, Kwang-Nak (Department of Nanofusion Technology, College of Nanoscience and Nanotechnology, Pusan National University) ;
  • Kang, Nam-Lyong (Department of Nanofusion Technology, College of Nanoscience and Nanotechnology, Pusan National University) ;
  • Lee, Jae-Beom (Department of Nanofusion Technology, College of Nanoscience and Nanotechnology, Pusan National University)
  • 투고 : 2012.01.04
  • 심사 : 2012.02.13
  • 발행 : 2012.05.20

초록

Singlet oxygen ($^1O_2$) is an important species for oxidation in biological processes. $^1O_2$ is implicated in the genotoxic effect, and plays an important role in the cell-signaling cascade and in the induction of gene expression. However, the rapid detection of $^1O_2$ in biological environments with sufficient specificity and sensitivity is hampered by its extremely low emission probability. Here, a layer-by-layer (LbL) film of CdTe quantum dots (QDs), polymers, and ascorbate have been designed as a rapid, highly selective, and sensitive fluorescence probe for $^1O_2$ detection. Upon reaction with $^1O_2$, the probe exhibits a strong photoluminescence (PL) response even at trace levels. This remarkable PL change should enable the probe to be used for $^1O_2$ detection in many chemical and biological systems and as an environmental sensor.

키워드

참고문헌

  1. Li, X.; Zhang, G.; Ma, H.; Zhang, D.; Li, J.; Zhu, D. J. Am. Chem. Soc. 2004, 126, 11543. https://doi.org/10.1021/ja0481530
  2. Manus-Spencer, L. A.; McNeill, K. J. Am. Chem. Soc. 2005, 127, 8954. https://doi.org/10.1021/ja052045b
  3. Song, B.; Wang, G.; Tan, M.; Yuan, J. J. Am. Chem. Soc. 2006, 128, 13442. https://doi.org/10.1021/ja062990f
  4. Tanaka, K.; Miura, T.; Umezawa, N.; Urano, Y.; Kikuchi, K.; Higuchi, T.; Nagano, T. J. Am. Chem. Soc. 2001, 123, 2530. https://doi.org/10.1021/ja0035708
  5. Yamakoshi, Y.; Umezawa, N.; Ryu, A.; Arakane, K.; Miyata, N.; Goda, Y.; Masumizu, T.; Nagano, T. J. Am. Chem. Soc. 2003, 125, 12803. https://doi.org/10.1021/ja0355574
  6. Ha, J. H.; Kim, M. S.; Kim, Y. R.; Jung, G. Y.; Lee, Y. H.; Shin, K. Bull. Korean Chem. Soc. 2001, 22, 63.
  7. Chin, K. K.; Trevithick-Sutton, C. C.; McCallum, J.; Jockusch, S.; Turro, N. J.; Scaiano, J. C.; Foote, C. S.; Garcia-Garibay, M. A. J. Am. Chem. Soc. 2008, 130, 6912. https://doi.org/10.1021/ja800926v
  8. Xu, K.; Wang, L.; Qiang, M.; Wang, L.; Li, P.; Tang, B. Chem. Commun. 2011, 47, 7386. https://doi.org/10.1039/c1cc12473k
  9. Aslan, K.; Geddes, C. D. In Metal-Enhanced Fluorescence; John Wiley & Sons, Inc.: 2010.
  10. Ragas, X.; Gallardo, A.; Zhang, Y.; Massad, W.; Geddes, C. D.; Nonell, S. J. Phys. Chem. C 2011, 115, 16275. https://doi.org/10.1021/jp202095a
  11. Toftegaard, R.; Arnbjerg, J.; Daasbjerg, K.; Ogilby, P.; Dmitriev, A.; Sutherland, D.; Poulsen, L. Angewandte Chemie International Edition 2008, 47, 6025. https://doi.org/10.1002/anie.200800755
  12. Zhang, Y.; Aslan, K.; Previte, M. J. R.; Geddes, C. D. Proceedings of the National Academy of Sciences 2008, 105, 1798. https://doi.org/10.1073/pnas.0709501105
  13. Ahmed, S.; Hong, S.; Lee, J. Frontiers of Materials Science 2011, 5, 40. https://doi.org/10.1007/s11706-011-0117-5
  14. Kramarenko, G. G.; Hummel, S. G.; Martin, S. M.; Buettner, G. R. Photochemistry and Photobiology 2006, 82, 1634. https://doi.org/10.1562/2006-01-12-RN-774
  15. Li, X.; Zhou, Y.; Zheng, Z.; Yue, X.; Dai, Z.; Liu, S.; Tang, Z. Langmuir 2009, 25, 6580. https://doi.org/10.1021/la900066z
  16. Gaponik, N.; Talapin, D. V.; Rogach, A. L.; Hoppe, K.; Shevchenko, E. V.; Kornowski, A.; Eychmüller, A.; Weller, H. J. Phys. Chem. B 2002, 106, 7177. https://doi.org/10.1021/jp025541k

피인용 문헌

  1. Luminescence-Based Optical Sensors Fabricated by Means of the Layer-by-Layer Nano-Assembly Technique vol.17, pp.12, 2017, https://doi.org/10.3390/s17122826