Women's Health Nursing (여성건강간호학회지)

Korean Society of Women Health Nursing (한국여성건강간호학회)
권호 표지
DOI QR코드

DOI QR Code

Experiences of Changes in Cognitive Function for Women treated with Chemotherapy for Breast Cancer

항암화학요법을 받은 유방암 여성의 인지기능변화 경험

  • Received : 2011.11.12
  • Accepted : 2012.02.03
  • Published : 2012.03.20
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: The purpose of this study was to describe the experiences of the process of the change in cognitive function for women treated with chemotherapy for breast cancer. Methods: There were ten participants in total in this study. Data were gathered utilizing in-depth interviews over 3 times from September 2010 to January 2011. Data were analyzed by employing Strauss and Corbin's (1998) grounded theory methodology. Results: Findings indicate that causal conditions of these results were 'side effects of chemotherapy' and 'menopausal state', including contextual conditions as, 'mental fatigue' and 'anxiety about recurrence'. The core category was identified as 'confronting with unexpected chaos'. Intervening conditions were 'support from other people', 'lack of information on cognitive impairment'. Interaction strategies were 'changing the habit of life', 'making efforts for living life' and 'seeking for medical information'. Consequences of the process were 'physical restriction', 'difficulty in social life', 'disturbed working ability' and 'psychological distress'. Conclusion: The results of this study show that nurses should recognize there is a notable difference between individual patient's contextual conditions and interactive strategies. Furthermore educational information and individualized intervention should be provided to improve cognitive function for women with breast cancer.

Keywords

References

  1. Bender, C. M., Paraska, K. K., Sereika, S. M., Ryan, C. M., & Berga, S. L. (2001). Cognitive function and reproductive hormones in adjuvant therapy for breast cancer: A critical review. Journal of Pain and Symptom Management, 21, 407-424. https://doi.org/10.1016/S0885-3924(01)00268-8
  2. Biglia, N., Moggio, G., Peano, E., Sgandurra, P., Ponzone, P., Nappi, R. E., et al. (2010). Effects of surgical and adjuvant therapies for breast cancer on sexuality, cognitive functions, and body weight. The Journal of Sexual Medicine, 7, 1891-1900. https://doi.org/10.1111/j.1743-6109.2010.01725.x
  3. Boykoff, N., Moieni, M., & Subramanian, S. K. (2009). Confronting chemobrain: An in-depth look at survivors' reports of impact on work, social networks, and health care response. Journal of Cancer Survivorship: Research and Practice, 3, 223-232. https://doi.org/10.1007/s11764-009-0098-x
  4. Brown, C. G. (2009). A guide to oncology symptom management. Pittsburgh, PA: Oncology Nursing Society.
  5. Collins, B., Mackenze, J., Stewart, A., Bielajew, C., & Verma, S. (2009). Cognitive effects of chemotherapy in post-menopausal breast cancer patients 1 year after treatment. Psycho-Oncology, 18, 134-143. https://doi.org/10.1002/pon.1379
  6. Debess, J., Riis, J. O., Pedersen, L., & Ewertz, M. (2009). Cognitive function and quality of life after surgery for early breast cancer in North Jutland, Denmark. Acta Oncologica, 48, 532-540. https://doi.org/10.1080/02841860802600755
  7. Fitch, M. I., Armstrong, J., & Tsang, S. (2008). Patient's experiences with cognitive changes after chemotherapy. Canadian Oncology Nursing Journal, 18, 180-192. https://doi.org/10.5737/1181912x184180185
  8. Ganz, P. A. (1998). Cognitive dysfunction following adjuvant treatment of breast cancer: A new dose-limiting toxic effect?. Journal of the National Cancer Institute, 90, 182-183. https://doi.org/10.1093/jnci/90.3.182
  9. Guba, E. G., & Lincoln, Y. S. (1989). Fourth generation evaluation. Newbury Park, CA: Sage Publications.
  10. Hermelink, K., Kuchenhoff, H., Untch, M., Bauerfeind, I., Lux, M. P., Buhner, M., et al. (2010). Two different side of 'Chemobrain': Determinants and nondeterminants of selfperceived cognitive dysfunction in a prospective, randomized, multicenter study. Psycho-Oncology, 19, 1321-1328. https://doi.org/10.1002/pon.1695
  11. Janelsins, M. C., Kohli, S., Mohile, S. G., Usuki, K., Ahles, T. A., & Morrow, G. R. (2011). An update on cancer-and chemotherapy- related cognitive dysfunction: Current status. Seminars in Oncology, 38, 431-438.
  12. Jansen, C. E., Cooper, B. A., Dodd, M. J., & Miaskowski, C. A. (2011). A prospective longitudinal study of chemotherapyinduced cognitive changes in breast cancer patients. Support Care Cancer, 19, 1647-1656. https://doi.org/10.1007/s00520-010-0997-4
  13. Jansen, C. E., Dodd, M., Miaskowski, C., Dowling, G. A., & Kramer, J. (2008). Preliminary results of a longitudinal study of changes in cognitive function in breast cancer patients undergoing chemotherapy with doxorubicin and cyclophosphamide. Psycho-Oncology, 17, 1189-1195. https://doi.org/10.1002/pon.1342
  14. Kim, S. H. (2005). Effects of individualized exercise program on cancer-related fatigue, physical and cognitive function, and emotional status in patients with gastric cancer during chemotherapy. Unpublished doctoral dissertation, Yonsei University, Seoul.
  15. Mitchell, T., & Turton, P. (2011). 'Chemobrain': Concentration and memory effects in people receiving chemotherapy-a descriptive phenomenological study. European Journal of Cancer Care, 20, 539-548.
  16. Mulrooney, T. (2007). The lived experience of cognitive impairment in women treated with chemotherapy for breast cancer. Unpublished doctoral dissertation, Utah University, Salt Lake, USA.
  17. Munir, F., Burrows, J., Yarker, J., Kalawsky, K., & Bains, M. (2010). Women's perceptions of chemotherapy-induced cognitive side effects on work ability: A focus group study. Journal of Clinical Nursing, 19, 1362-1370. https://doi.org/10.1111/j.1365-2702.2009.03006.x
  18. Paraska, K., & Bender, C. M. (2003). Cognitive dysfunction following adjuvant chemotherapy for breast cancer: Two case studies. Oncology Nursing Forum, 30, 473-478.
  19. Raffa, R. B., Duong, P. V., Finney, J., Garber, D. A., Lam, L. M., Mathew, S. S., et al. (2006). Is 'chemo-fog'/'chemo-brain' caused by cancer chemotherapy? Journal of Clinical Pharmacy and Therapeutics, 31, 129-138. https://doi.org/10.1111/j.1365-2710.2006.00726.x
  20. Reid-Arndt, S. A., Yee, A., Perry, M. C., & Hsieh, C. (2009). Cognitive and psychological factors associated with early posttreatment functional outcomes in breast cancer survivors. Journal of Psychosocial Oncology, 27, 415-434. https://doi.org/10.1080/07347330903183117
  21. Rottok, J., & Ross, B. (1994). Cognitive rehabilitation. Washington DC: American Psychiatric Press.
  22. Schagen, S. B., Das, E., & van Dam, F. S. (2009). The influence of priming and pre-existing knowledge of chemotherapyassociated cognitive complaints on the reporting of such complaints in breast cancer patients. Psycho-Oncology, 18, 674-678. https://doi.org/10.1002/pon.1454
  23. Shockney, L. D. (2009). Breast cancer survivorship care: A resource for nurses. Sudbury, MA: Jones and Bartlett.
  24. Stewart, A., Collins, B., Mackenzie, J., Tomiak, E., Verma, S., & Bielajew, C. (2008). The cognitive effects of adjuvant chemotherapy in early stage breast cancer: A prospective study. Psycho-Oncology, 17, 122-130. https://doi.org/10.1002/pon.1210
  25. Strauss, A., & Corbin, J. (1998). Basic of qualitative research: Techniques and procedures for developing grounded theory. Thousand Oaks, CA: Sage.
  26. van Dam, F. S., Schagen, S. B., Muller, M. J., Boogerd, W., vd Wall, E., Droogleever Fortuyn, M. E., et al. (1998). Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: High-dose versus standard-dose chemotherapy. Journal of the National Cancer Institute, 90, 210-218. https://doi.org/10.1093/jnci/90.3.210
  27. Vearncombe, K. J., Rolfe, M., Wright, M., Pachana, N. A., Andrew, B., & Beadle, G. (2009). Predictors of cognitive decline after chemotherapy in breast cancer patients. Journal of the International Neuropsychological Society, 15, 951-962. https://doi.org/10.1017/S1355617709990567
  28. Wefel, J. S., Saleeba, A. K., Buzdar, A. U., & Meyers, C. A. (2010). Acute and late onset cognitive dysfunction associated with chemotherapy in women with breast cancer. Cancer, 116, 3348-3356. https://doi.org/10.1002/cncr.25098