Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report

  • Yoon, Yong-Han (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Kim, Jae-Ho (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Kim, Kwang-Ho (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Baek, Wan-Ki (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Lee, Hyun-Kyu (Department of Hematology and Oncology, Inha University Hospital, Inha University School of Medicine) ;
  • Lee, Moon-Hee (Department of Hematology and Oncology, Inha University Hospital, Inha University School of Medicine) ;
  • Lee, Kyung-Hee (Department of Diagnostic Radiology, Inha University Hospital, Inha University School of Medicine) ;
  • Kim, Lucia (Department of Pathology, Inha University Hospital, Inha University School of Medicine)
  • Received : 2011.08.12
  • Accepted : 2011.11.11
  • Published : 2012.02.05
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Abstract

A large cell neuroendocrine carcinoma (LCNEC) of the thymus is a very rare malignant tumor that has a very poor prognosis. The detailed clinical features of LCNEC are still unknown, including the long term prognoses and the definitive modalities of the treatment for LCNEC of the thymus. We are reporting 2 cases of an enlarged LCNEC of the thymus, both of which were diagnosed and treated by surgical resection followed by postoperative adjuvant chemoradiation therapy. Although recurrences and metastases of the LCNEC were noticed 1 and 4 years postoperatively for each case, aggressive surgical resection and adjuvant chemoradiation therapy may be helpful for a patient's long term survival.

Keywords

References

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