생약학회지 (Korean Journal of Pharmacognosy)

  • 제43권4호
  • /
  • Pages.291-296
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  • 2012
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  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

바디나물과 백화전호 뿌리 정유의 비교 연구

Study on the Essential Oils from the Roots of Angelica decursiva and Peucedanum praeruptorum

  • 임혜림 (덕성여자대학교 약학대학) ;
  • 신승원 (덕성여자대학교 약학대학)
  • Lim, Hyerim (College of Pharmacy, Duksung Women's University) ;
  • Shin, Seungwon (College of Pharmacy, Duksung Women's University)
  • 투고 : 2012.11.23
  • 심사 : 2012.12.04
  • 발행 : 2012.12.31
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초록

The dried roots of Angelica decursiva and Peucedanum praeruptorum are registered as the official sources for the drug 'Junho' in Korean Herbal Pharmacopoeia. In this study the essential oils were extracted from the roots of the two plants by steam distillation. Their compositions and the biological activities were compared. As the results of GC and GC-MS analysis, forty one and thirty five compounds were identified in the essential oils of Angelica decursiva and Peucedanum praeruptorum, respectively. Both of the two essential oils contained ${\alpha}$-pinene as the most abundant component. They showed similar significant antioxidant activities in DPPH scavenging assay, and reducing power test. Their dose dependent inhibitions of the nitrosamine formation were identified in experiment using BHA as control. In MTT test of three cancer cell lines, HeLa, MCF-7 and SK-Hep-1, the essential oil from A. decursiva showed stronger activities than that of P. praeruptorum and their common main component, ${\alpha}$-pinene.

키워드

참고문헌

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