Noise Phobia-Induced Relative Polycythemia in a Dog

개에서 소리공포증에 의해 발생한 상대적 적혈구증가증 증례

  • Kang, Min-Hee (College of Veterinary Medicine and Veterinary Science Research Institute, Konkuk University) ;
  • Park, Hee-Myung (College of Veterinary Medicine and Veterinary Science Research Institute, Konkuk University)
  • 강민희 (건국대학교 수의과대학, 수의과학연구소) ;
  • 박희명 (건국대학교 수의과대학, 수의과학연구소)
  • Accepted : 2012.12.18
  • Published : 2012.12.31

Abstract

A 6-year-old castrated male Miniature Pinscher dog was referred due to shaking, panting and inappropriate elimination during thunderstorms. The dog had noise phobia after a car accident two years ago. The intensity of the fear of noise, especially with thunderstorms, worsened during the past 3 months (thunderstorm season). Physical examination revealed hyperthermia, tachypnea (panting), mild tachycardia, and an elevated systolic blood pressure. Laboratory examination revealed mild polycythemia with a lower oxygen pressure and saturation. Based on the history, physical examination, and laboratory tests, the dog was diagnosed as a noise phobia concurrent with relative polycythemia. Treatment was initiated with behavior modification with desensitization, counter-conditioning, and medication. Music therapy was also used and appeared to be beneficial. Clinical signs including polycythemia are improved. This case indicates that relative polycythemia can be occurred by chronic mental stress, such as noise phobia in a dog.

6년령의 수컷 미니어쳐 핀셔견이 천둥소리로 인한 떨림, 빈호흡 및 부적절한 배뇨를 주증으로 내원하였다. 환축은 2년전 발생한 교통사고 이후 큰 소리에 공포감을 가지게 되었으며, 이는 천둥 발생이 잦은 지난 3개월간 지속적으로 나빠졌다. 기본 신체검사에서 미열, 빈호흡, 빈맥과 함께 혈압의 상승이 확인되었다. 실험실 검사에서 동맥혈의 산소포화도 감소와 함께 적혈구증가증이 확인되었다. 병력, 신체검사 및 실험실적 검사를 바탕으로 본 환축은 소리공포증과 함께 발생한 상대적 적혈구증가증으로 진단 되었다. 증상의 완화를 위하여, 행동교정 및 탈감각화, 반대조건화, 그리고 약물치료가 시작되었다. 다른 치료들과 함께 음악치료도 병행되었으며, 치료기간 중 임상증상 및 적혈구증가증이 개선되었다. 따라서, 본 증례는 소리공포증과 같은 만성적인 스트레스에 의하여 발생한 상대적 적혈구증가증의 진단증례 보고 이다.

Keywords

References

  1. Benitone J, Kling A. Polycythemia of stress in psychiatric hospital populations. J Psychrosom Res 1970; 14: 105-108. https://doi.org/10.1016/0022-3999(70)90075-9
  2. Campbell KL. Diagnosis and management of polycythemia in dogs. Comp Cont Ed Pract Vet 1990; 12: 543-550.
  3. Chlan L. Effectiveness of a music therapy intervention on relaxation and anxiety for patients receiving ventilatory assistance. Heart Lung 1998; 27: 196-176.
  4. Crow SE, Allen DP, Murphy CJ, Culbertson R. Concurrent renal adenocarcinoma and polycythemia in a dog. J Am Anim Hosp Assoc 1995; 31: 29-33. https://doi.org/10.5326/15473317-31-1-29
  5. Crowell-Davis SL, Seibert LM, Sung W, Parthasarathy V, Curtis TM. Use of clomipramine, alprazolam, and behavior modification for treatment of strom phobia in dogs. J Am Vet Med Assoc 2003; 222: 744-748. https://doi.org/10.2460/javma.2003.222.744
  6. El-Yousef MK, Bakewell WE Jr. Stress polycythemia-a pathophysiologic study. South Med J 1975; 68: 559-564. https://doi.org/10.1097/00007611-197505000-00010
  7. Gray HE, Weigand GM, Cottrill NB, Willis MA, Morgan RV. Polycythemia vera in a dog presenting with uveitis. J Am Anim Hosp Assoc 2003; 39: 355-360. https://doi.org/10.5326/0390355
  8. Haghighat R, Costa DC, Chesser E. Polycythemia and agoraphobia. J Behav Ther Exp Psychiatry 1996; 27: 149-155. https://doi.org/10.1016/0005-7916(96)00006-7
  9. Irimajiri M, Jay EE, Glickman LT, Leuscher AU. Mild polycythemia associated with compulsive disorder in dogs. J Vet Behavior 2006; 1: 23-28. https://doi.org/10.1016/j.jveb.2006.04.010
  10. Kuwahira I, Kamiya U, Iwamoto T, Moue Y, Urano T, Ohta Y, Gonzalez NC. Splenic contraction-induced reversible increase in hemoglobin concentration in intermittent hypoxia. J Appl Physiol 1999; 86: 181-187. https://doi.org/10.1152/jappl.1999.86.1.181
  11. McCobb EC, Brown EA, Damiani K, Dodman NH. Thunderstorm phobia in dogs: an internet survey of 69 cases. J Am Anim Hosp Assoc 2001; 37: 319-324. https://doi.org/10.5326/15473317-37-4-319
  12. Mok E, Wong KY. Effects of Music on patient anxiety. Aorn J 2003; 77: 396-410. https://doi.org/10.1016/S0001-2092(06)61207-6
  13. Nitsche EK. Erythrocytosis in dogs and cats: diagnosis and management. Comp Cont Ed Pract Vet 2004; 26: 104-118.
  14. Overall KK, Dunham AE, Frank D. Frequency of nonspecific clinical signs in dogs with separation anxiety, thunderstorm phobia, and noise phobia, alone or in combination. J Am Vet Med Assoc 2001; 219: 467-473. https://doi.org/10.2460/javma.2001.219.467
  15. Overall KL. Fears, anxieties and stereotypies. In: Clinical behavioral medicine for small animals. St Louis: Mosby. 1997:209-250.
  16. Petterson SM, Gottdiener JS, Hecht G, Vargot S, Krantz DS. Effects of acute mental stress on serum lipids: mediating effects of plasma volume. Psychosom Med 1993; 55: 525-632. https://doi.org/10.1097/00006842-199311000-00008
  17. Quesnel AD, Kruth SA. Polycythemia vera and glomerulonephritis in a dog. Can Vet J 1992; 33: 671-672.
  18. Sausser S, Waller RJ. A model for music therapy with students with emotional and behavioral disorders. Art Psychotherapy 2006; 33: 1-10. https://doi.org/10.1016/j.aip.2005.05.003
  19. Seksel K, Lindeman MJ. Use of clomipramine in treatment of obsessive-compulsive disorder, separation anxiety and noise phobia in dogs: a preliminary, clinical study. Aust Vet J 2001; 79: 252-256. https://doi.org/10.1111/j.1751-0813.2001.tb11976.x
  20. Shull-Selcer E, Stagg W. Advances in the understanding and treatment of noise phobias. Vet Clin North Am 1991;21: 353-367. https://doi.org/10.1016/S0195-5616(91)50038-3
  21. Voith VL, Borchelt PL. Behavioral aspects of selecting and raising dogs and cats. Comp Cont Ed Pract Vet 1985; 7:209-217.
  22. Wells DL, Graham L, Hepper GL. The influence of auditory stimulation of the behavior of dogs housed in a rescue shelter. Anim Welf 2002; 11: 385-393.