한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제29권6호
  • /
  • Pages.431-434
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  • 2012
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

제주도 더러브렛 종에서 신생마 적혈구용혈증을 유발하는 적혈구 표면 항원 조사

Red Blood Cell Surface Antigens Responsible for Neonatal Isoerythrolysis in Thoroughbred Horses of Jeju Island

  • 송정환 (제주대학교 수의과대학) ;
  • 윤영민 (제주대학교 수의과대학) ;
  • 최귀철 (한국마사회 제주 경주마 육성목장) ;
  • 이용덕 (한국마사회 제주 경주마 육성목장) ;
  • 정지훈 (한국마사회 제주 경주마 육성목장) ;
  • 이경갑 (제주대학교 수의과대학)
  • 심사 : 2012.12.03
  • 발행 : 2012.12.31
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초록

본 연구의 목적은 제주도 내 더러브렛 경주마에서 신생마 동종면역성 적혈구 용혈증과 가장 밀접한 연관이 있다고 보고된 적혈구 항원 Aa, Ca, Qa의 발현 빈도를 확인하고자 하였다. 본 실험은 제주도 내에서 사육되고 있는 종빈마와 종모마 총 262두의 혈액에서 분리한 2% 적혈구 부유액이 사용되었으며, 간접 항체 검사을 통해 결과를 확인하였다. 226 두의 종빈마 중 Aa 음성이 9 두 (3.98%), Ca 음성이 8 두 (3.54%), Qa 음성이 17두 (7.52%)로 나타났으며, 36 두의 종모마 중 Aa 음성이 1두 (2.78%), Ca 음성이 3두 (8.33%), Qa 음성이 3두 (8.33%)로 확인되었다. 이들 결과를 토대로, 향후 말 번식에 있어서 종부 파트너 선택에 중요한 기초 자료를 제시하고 나아가 신생마 동종면역성 용혈성 빈혈 예방에 기여할 것으로 기대된다.

This study was conducted to survey red blood cell (RBC) antigens Aa, Ca and Qa types, which are considered to be the most significantly associated with occurrence of neonatal isoerythrolysis, and the results are expected to provide valuable informations in organization of breeding plan, hence preventing the disease. Blood samples were collected from 262 Thoroughbred horses in Jeju island. Two percent cell suspension has been prepared from each sample and they were tested by indirect antiglobulin test. Of the 226 mare's samples, 9(3.98%) were Aa negative, 8(3.54%) were Ca negative, 17(7.52%) were Qa negative. Of the 36 Stallion's samples, 1(2.78%) was Aa negative, 3(8.33%) were Ca negative, 3(8.33%) were Qa negative. On the basis of these data, a database for breeding compatability could be set, and it would play an important role as a reference for arranging the mating partners.

키워드

참고문헌

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