한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)

  • 제27권4호
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  • Pages.461-465
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  • 2012
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  • 1229-1153(pISSN)
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  • 2465-9223(eISSN)
한국식품위생안전성학회 (The Korean Society of Food Hygiene and Safety)
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추출용매에 따른 브로콜리의 항산화와 항염증에 대한 효과

Effects of Broccoli on Anti-inflammation and Anti-oxidation According to Extraction Solvent

  • 장민우 (신라대학교 의생명과학대학 생명공학과) ;
  • 하배진 (신라대학교 의생명과학대학 생명공학과)
  • Jang, Min-Woo (Department of Biotechnology, College of Medical Life Science, Silla University) ;
  • Ha, Bae-Jin (Department of Biotechnology, College of Medical Life Science, Silla University)
  • 투고 : 2012.09.20
  • 심사 : 2012.12.03
  • 발행 : 2012.12.31
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초록

본 실험에서는 여드름 치료에 사용되던 국소 레티노이드제와 항생제를 대용 할 수 있고 화장품에 사용되는 원료로 추출하여 항여드름 치료제 또는 화장품 원료를 개발하기 위해 실험한 결과 broccoli proplyeneglycol 그룹에서 DPPH, superoxide radical, nitric oxide assay 에서 모두 vitamin C에 가까운 활성을 나타내었고 paper disk diffusion test에서는 broccoli ethanol과 broccoli hexane 그룹에서 P. acne의 저해 활성을 나타낸 것으로 보아 항여드름 치료제 또는 화장품 원료로써의 유용 가치가 있다고 사료 되어진다.

Broccoli has a functional substance, sulforaphane that has effects of anticancer, antioxidant, antimicrobial and anti-inflammatory. Sulforaphane, one of the hydrolysis products of glucoraphanin in broccoli, cabbage and kale, was contributed to the role of antioxidant. Broccoli contains a number of bioactive compounds including glucosinolates, S-methyl cysteine sulfoxide and many antioxidants. The ethanol extract (BE), hexane extract (BH), propylene glycol extract (BP) and butylenesglycol extract (BB) of broccoli were used to investigate the antioxidation and anti-inflammatory effects of sulforaphane extracts from broccoli. The high scavenging abilities of DPPH, $O_2{^-}$ were observed. Also sulforaphane extracts from broccoli showed the inhibition effect on NO rate. These results demonstrated that sulforaphane extracts from broccoli could be useful as an antioxidation and anti-inflammatory functional ingredient.

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피인용 문헌

  1. Quality and Antioxidant Properties of White Breads Enhanced with Broccoli (Brassica oleracea L.) Powder vol.31, pp.5, 2015, https://doi.org/10.9724/kfcs.2015.31.5.614
  2. Comparative analysis of individual glucosinolates, phytochemicals, and antioxidant activities in broccoli breeding lines vol.57, pp.4, 2016, https://doi.org/10.1007/s13580-016-0088-7
  3. Effects of Mandarin, Broccoli, Cabbage, and Carrot Concentrate on in Vitro Biological Activities of Lactic Acid Bacteria-Fermented Cereal Mixtures of Rice Bran and Germinated Barley vol.33, pp.6, 2017, https://doi.org/10.9724/kfcs.2017.33.6.662