Korean Circulation Journal

  • 제42권9호
  • /
  • Pages.592-594
  • /
  • 2012
  • /
  • 1738-5520(pISSN)
  • /
  • 1738-5555(eISSN)
대한심장학회 (The Korean Society of Cardiology)
권호 표지
DOI QR코드

DOI QR Code

Anti-Inflammatory Effects of Statins Beyond Cholesterol Lowering

  • Joo, Seung-Jae (Cardiology Division, Department of Internal Medicine, Jeju National University Hospital)
  • 발행 : 2012.09.30
⟨ 이전 논문 다음 논문 ⟩

초록

키워드

참고문헌

  1. Baigent C, Keech A, Kearney PM, et al. Efficacy and safety of cholesterol- lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 2005;366: 1267-78. https://doi.org/10.1016/S0140-6736(05)67394-1
  2. LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005; 352:1425-35. https://doi.org/10.1056/NEJMoa050461
  3. Mizuno Y, Jacob RF, Mason RP. Inflammation and the development of atherosclerosis. J Atheroscler Thromb 2011;18:351-8. https://doi.org/10.5551/jat.7591
  4. Danesh J, Wheeler JG, Hirschfield GM, et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 2004;350:1387-97. https://doi.org/10.1056/NEJMoa032804
  5. Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 2010;375:132-40. https://doi.org/10.1016/S0140-6736(09)61717-7
  6. Blum A, Shamburek R. The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis. Atherosclerosis 2009;203:325-30. https://doi.org/10.1016/j.atherosclerosis.2008.08.022
  7. Nissen SE, Tuzcu EM, Schoenhagen P, et al. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med 2005; 352:29-38. https://doi.org/10.1056/NEJMoa042000
  8. Robinson JG, Smith B, Maheshwari N, Schrott H. Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. J Am Coll Cardiol 2005;46:1855-62. https://doi.org/10.1016/j.jacc.2005.05.085
  9. Kinlay S. Low-density lipoprotein-dependent and -independent effects of cholesterol-lowering therapies on C-reactive protein: a meta-analysis. J Am Coll Cardiol 2007;49:2003-9. https://doi.org/10.1016/j.jacc.2007.01.083
  10. Cannon CP, Steinberg BA, Murphy SA, Mega JL, Braunwald E. Metaanalysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy. J Am Coll Cardiol 2006;48:438-45. https://doi.org/10.1016/j.jacc.2006.04.070
  11. Peters SA, Palmer MK, Grobbee DE, et al. C-reactive protein lowering with rosuvastatin in the METEOR study. J Intern Med 2010;268:155-61. https://doi.org/10.1111/j.1365-2796.2010.02230.x
  12. Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008;359:2195-207. https://doi.org/10.1056/NEJMoa0807646
  13. Ridker PM, MacFadyen J, Libby P, Glynn RJ. Relation of baseline highsensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Am J Cardiol 2010; 106:204-9. https://doi.org/10.1016/j.amjcard.2010.03.018
  14. Kim YR, Park JH, Lee HJ, Pyun WB, Park SH. The effect of doubling the statin dose on pro-inflammatory cytokine in patients with triple-vessel coronary artery disease. Korean Circ J 2012;42:595-9. https://doi.org/10.4070/kcj.2012.42.9.595
  15. Ridker PM, Cannon CP, Morrow D, et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005;352:20-8. https://doi.org/10.1056/NEJMoa042378
  16. Ridker PM, Danielson E, Fonseca FA, et al. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 2009;373: 1175-82. https://doi.org/10.1016/S0140-6736(09)60447-5

피인용 문헌

  1. Differential Metabolic Actions of Specific Statins: Clinical and Therapeutic Considerations vol.20, pp.8, 2012, https://doi.org/10.1089/ars.2013.5531
  2. Statins and Renin-Angiotensin System Inhibitor Combination Treatment to Prevent Cardiovascular Disease vol.78, pp.2, 2012, https://doi.org/10.1253/circj.cj-13-1494
  3. Comparison of Lipid Profile, Liver Enzymes, Creatine Kinase and Lactate Dehydrogenase Among Type II Diabetes Mellitus Patients on Statin Therapy vol.13, pp.None, 2020, https://doi.org/10.2147/dmso.s234382