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Candida Arthritis Presenting as a Huge Popliteal Cyst in a Patient with Rheumatoid Arthritis: A Case Report and Review of the Literature

류마티스 관절염 환자에서 슬와부 낭종으로 발현된 칸디다 관절염 1예

  • Hwang, Hyun-Sik (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Kim, Hyun-Hee (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Kim, Hong-Ik (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Baek, Seung-Hoon (Department of Orthopaedic Surgery, Catholic University of Daegu School of Medicine) ;
  • Park, Sung-Hoon (Department of Internal Medicine, Catholic University of Daegu School of Medicine) ;
  • Choe, Jung-Yoon (Department of Internal Medicine, Catholic University of Daegu School of Medicine)
  • 황현식 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 김현희 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 김홍익 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 백승훈 (대구가톨릭대학교 의과대학 정형외과학교실) ;
  • 박성훈 (대구가톨릭대학교 의과대학 내과학교실) ;
  • 최정윤 (대구가톨릭대학교 의과대학 내과학교실)
  • Published : 2012.01.01

Abstract

Candida arthritis is an uncommon cause of infectious arthritis that can occur in immunocompromised patients, such as those with rheumatoid arthritis. Candida arthritis arises in two ways: from direct inoculation or hematogenous dissemination. Direct inoculation is common in immunocompromised hosts during intra-articular injection or surgical procedures. The affected joints are generally swollen, tender, and mildly warm, with no evidence of disseminated candidiasis. Reported treatments include intravenous amphotericin B administration and drainage, or the use of 5-fluocytosine or ketoconazole to decrease amphotericin B toxicity. Surgical treatment has been necessary in some cases to eradicate candidal infection. Here, we report a case of candida arthritis combined with a huge popliteal cyst in a patient with rheumatoid arthritis and present a review of the relevant literature.

칸디다 관절염은 드문 질환이나 류마티스 관절염 환자와 같은 면역저하자에게 생길 수 있다. 감염 경로는 진균의 직접침범과 혈행을 통한 감염으로 나뉘는데 직접침범의 경우 면역저하자가 관절강내 주사를 맞은 후 또는 관절 수술 후 생길 수 있으며 전신증상 없이 국소 관절부위의 부종, 통증 정도의 증상만 있는 경우가 흔하다. 진단은 관절액 배양검사를 통해 가능하다. 치료는 amphotericin B 정맥주사와 배액이 주로 이용되고 fluconazole 또는 5-fluocytosine을 사용하기도하며 수술적 치료를 시행하는 경우도 있다.

Keywords

References

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