The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Medical Management of Acute Kidney Injury, Mainly Focused on Preventable Diseases

급성 신손상의 내과적 치료: 예방이 가능한 질환 중심으로

  • OH, Dong-Jin (Division of Nephrology, Department of Internal Medicine, Chung-Ang University College of Medicine)
  • 오동진 (중앙대학교 의과대학 내과학교실 신장내과)
  • Published : 2012.01.01
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Abstract

Acute kidney injury (AKI) severity predicts adverse outcomes, such as requirement for renal replacement therapy, length of hospital stay, and mortality. In addition, the widespread use of the RIFLE (risk, injury, failure, loss of kidney function, end-stage kidney disease) and AKI classification systems has shown that even small changes in glomerular filtration rate are associated with increased mortality. Furthermore, AKI contributes to dysfunction of other organs, such as heart, lung, brain, and liver. Consequently, primary/secondary prevention and early diagnosis of AKI are of central clinical importance. Herein, I briefly reviewed the established medical management of AKI, mainly focused on preventable diseases.

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References

  1. Nash K, Hafeez A, Hou S. Hospital-acquired renal insufficiency. Am J Kidney Dis 2002;39:930-936. https://doi.org/10.1053/ajkd.2002.32766
  2. Bartholomew BA, Harjai KJ, Dukkipati S, et al. Impact of nephropathy after percutaneous coronary intervention and a method for risk stratification. Am J Cardiol 2004;93:1515-1519. https://doi.org/10.1016/j.amjcard.2004.03.008
  3. Gonzalez NC, Wood JG. Leukocyte-endothelial interactions in environmental hypoxia. Adv Exp Med Biol 2001;502:39-60.
  4. Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990;186:1-85.
  5. Pryor WA, Squadrito GL. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol 1995;268:L699-L722.
  6. Merten GJ, Burgess WP, Gray LV, et al. Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial. JAMA 2004;291:2328-2334. https://doi.org/10.1001/jama.291.19.2328
  7. Palevsky PM, Murray PT. Acute kidney injury and critical care nephrology. NephSAP 2006;5:81-84.
  8. Palevsky PM, Murray PT. Acute kidney injury and critical care nephrology (Myoglobinuric AKI). NephSAP 2006;5: 94-96.
  9. Palevsky PM. Acute renal failure. NephSAP 2004;3:245-284.
  10. Gunal AI, Celiker H, Dogukan A, et al. Early and vigorous fluid resuscitation prevents acute renal failure in the crush victims of catastrophic earthquakes. J Am Soc Nephrol 2004;15:1862-1867. https://doi.org/10.1097/01.ASN.0000129336.09976.73
  11. Macedo E, Bouchard J, Mehta RL. Prevention and nondialytic management of acute kidney injury. In: Floege J, Johnson RJ, Feehally J, eds. Comprehensive Clinical Nephrology. 4th ed. St. Louis: Elsevier Saunders, 2010: 830-842.
  12. Palevsky PM, Murray PT. Acute kidney injury and critical care nephrology (Medication-associated AKI). NephSAP 2006;5:98-100.
  13. Palevsky PM, Murray PT. Acute kidney injury and critical care nephrology (Malignancy-associated AKI). NephSAP 2006;5:96-98.
  14. Sharfuddin AA, Weisbord SD, Palevsky PM, Molitoris BA. Acute kidney injury. In: Taal MW, Chertow GM, Marsden PA, Skorecki K, Yu AS, Brenner BM, eds. Brenner & Rector's The Kidney. 9th ed. Philadelphia: Saunders, 2011:1044-1099.

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