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A Case of Therapy-Related Acute Myeloid Leukemia Following 5-Fluorouracil Chemotherapy

  • Park, Hye-Jeong (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Choi, Jung-Hye (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Lee, Kyeong-A (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, Hyun-Cheol (Department of Internal Medicine, Hanyang University College of Medicine) ;
  • Nam, Young-Soo (Department of Surgery, Hanyang University College of Medicine) ;
  • Oh, Young-Ha (Department of Pathology, Hanyang University College of Medicine) ;
  • Lee, Woong-Soo (Department of Laboratory Medicine, Hanyang University College of Medicine)
  • Published : 2012.03.01

Abstract

Keywords

References

  1. Larson RA. Etiology and management of therapy-related myeloid leukemia. Hematology Am Soc Hematol Educ Program 2007;2007:453-459. https://doi.org/10.1182/asheducation-2007.1.453
  2. Turker A, Guler N. Therapy related acute myeloid leukemia after exposure to 5-fluorouracil: a case report. Hematol Cell Ther 1999;41:195-196. https://doi.org/10.1007/s00282-999-0195-3
  3. Smith SM, Le Beau MM, Huo D, et al. Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series. Blood 2003;102:43-52. https://doi.org/10.1182/blood-2002-11-3343
  4. Le Beau MM, Albain KS, Larson RA, et al. Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7. J Clin Oncol 1986;4:325-345. https://doi.org/10.1200/JCO.1986.4.3.325
  5. Yin CC, Cortes J, Barkoh B, Hayes K, Kantarjian H, Jones D. t(3;21)(q26;q22) in myeloid leukemia: an aggressive syndrome of blast transformation associated with hydroxyurea or antimetabolite therapy. Cancer 2006;106:1730-1738. https://doi.org/10.1002/cncr.21797

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  1. Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines vol.8, pp.62, 2012, https://doi.org/10.18632/oncotarget.20501
  2. A Case of Therapy-related Acute Myeloid Leukemia Following Treatment with 5-Fluorouracil vol.10, pp.12, 2012, https://doi.org/10.7759/cureus.3769