Physical Therapy Korea (한국전문물리치료학회지)

Korean Research Society of Physical Therapy (한국전문물리치료학회)
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Effects of a Rehabilitation Program on Quality of Life, Cardiopulmonary Function and Fatigue During Radiotherapy for Breast Cancer Patients

유방암 환자의 방사선 치료 기간 동안 재활치료 프로그램이 삶의 질, 심폐기능, 피로에 미치는 영향

  • Do, Jung-Hwa (Team of Physical Medicine & Rehabilitation, Asan Medical Center) ;
  • Seong, Jun-Hyuk (Team of Physical Medicine & Rehabilitation, Asan Medical Center) ;
  • Ahn, Jun-Su (Team of Physical Medicine & Rehabilitation, Asan Medical Center) ;
  • Cho, Young-Ki (Team of Physical Medicine & Rehabilitation, Asan Medical Center)
  • 도정화 (서울아산병원 재활의학팀) ;
  • 성준혁 (서울아산병원 재활의학팀) ;
  • 안준수 (서울아산병원 재활의학팀) ;
  • 조영기 (서울아산병원 재활의학팀)
  • Received : 2011.08.01
  • Accepted : 2011.09.26
  • Published : 2012.02.19
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Abstract

This study examines the effects of a rehabilitation program on quality of life (QOL), cardiopulmonary function and fatigue during radiotherapy for breast cancer patients. The program includes aerobic exercise, stretching and strengthening exercises. Sixty-five women participated in this study and they were asked to perform supervised exercises that last for 60 minutes five times a week for six weeks. The European organization for research and treatment of cancer-cancer (EORTC QLQ-C30) and the breast (EORTC QLQ-BR23), predicted maximal volume of oxygen consumption ($VO_{2max}$) and fatigue severity scale (FSS) were assessed before and after the rehabilitation program. The 60-minute program consisted of a 10-minute warm-up, 30-minute of aerobic exercises, and 15-minute of strengthening exercises, followed by a five-minute cool-down. Heart rates were monitored throughout the exercise class to ensure that patients were exercising at the target heart rate of 40~75% of the age-adjusted heart rate maximum. There were statistically significant differences in the changes of physical function and cancer related symptoms in the EORTC QLQ-C30 and EORTC QLQ-BR23 (p<.05). There was a statistically significant improvement in the predicted $VO_{2max}$ (p<.05), although there were no significant differences in the FSS (p>.05). The results of our study suggest that a supervised rehabilitation program may benefit the physical aspects and QOL of patients receiving radiotherapy for breast cancer.

Keywords

References

  1. 박용균. 최대 산소소모량 평가에 있어서 자전거 에르고미터를 이용한 최대하부하 검사방법의 타당도. 고신대학교 대학원. 석사학위논문, 2006.
  2. 보건복지가족부. 2009년 국가암 등록통계 결과 발표. 국립암센터 중앙암등록본부. 2009.
  3. 윤영호. 부인암환자의 삶의 질 평가 및 연구. 대한부인종양콜포스코피학회지. 2005;16(3):182-188.
  4. 조옥희. 유방절제술 환자를 위한 통합적 재활프로그램의 효과. 대한간호학회지. 2004;34(5);809-819.
  5. 정규인, 송찬희. 피로와 우울, 불안증 환자에서 fatigue severity scale의 임상적 유용성. 정신신체의학. 2001;9(2):164-173.
  6. Beaulac SM, McNair LA, Scott TE. et al. Lymph edema and quality of life in survivors of early stage breast cancer. Arch Surg. 2002;137(11):1253-1257. https://doi.org/10.1001/archsurg.137.11.1253
  7. Byar KL, Berger AM, Bakken SL, et al. Impact of adjuvant breast cancer chemotherapy on fatigue, other symptoms, and quality of life. Oncol Nurs Forum. 2006;33(1):E18-E26. https://doi.org/10.1188/06.ONF.E18-E26
  8. Campbell A, Mutrie N, White F, et al. A pilot study of a supervised group exercise programme as a rehabilitation treatment for women with breast cancer receiving adjuvant treatment. Eur J Oncol Nurs. 2005;9(1):56-63. https://doi.org/10.1016/j.ejon.2004.03.007
  9. Chae YR, Choe MA. Effects of exercise on cardiopulmonary functions and shoulder joint functioning in Breast Cancer patients undergoing radiation therapy after breast surgery. Jr Korean Acad Nurs. 2001;31(3),454-466. https://doi.org/10.4040/jkan.2001.31.3.454
  10. Courneya KS, Friedenreich CM, Sela RA, et al. The group psychotherapy and home-based physical exercise(group-hope) trial in cancer survivors: Physical fitness and quality of life outcome. Psychooncology. 2003;12(4):357-374. https://doi.org/10.1002/pon.658
  11. Crowley SA. The effect of a structured exercise program on fatigue, strength, endurance, physical self-efficacy, and functional wellness in women with early stage breast cancer. Ann Arbor, MI, University of Michigan, 2003:127.
  12. Fairey AS, Courneya KS, Field CJ, et al.. Physical exercise and immune system function in cancer survivors: A comprehensive review and future directions. Cancer. 2002;94(2):539-551. https://doi.org/10.1002/cncr.10244
  13. Helgeson VS, Cohen S, Schulz R, et al. Education and peer discussion group interventions and adjustment to breast cancer. Arch Gen Psychiatry. 1999;56(4):340-347. https://doi.org/10.1001/archpsyc.56.4.340
  14. Holmberg L, Norden T, Lindgren A, et al. Pre-operative oestradiol levels-relation to survival in breast cancer. Eur J Surg Oncol. 2001; 27(2):152-156. https://doi.org/10.1053/ejso.2000.1084
  15. Hwang JH, Chang HJ, Shim YH, et al. Effect of supervised exercise therapy in patients receiving radiotherapy for breast cancer. Yonsei Med J. 2008;49(3);443-450. https://doi.org/10.3349/ymj.2008.49.3.443
  16. Jereczek-Fossa BA, Marsiglia HR, Orecchia R. Radiotherapy-related fatigue: How to assess and how to treat the symptom. A commentary. Tumori. 2001;87(3):147-151.
  17. Jereczek-Fossa BA, Marsiglia HR, Orecchia R. Radiotherapy-related fatigue. Crit Rev Oncol Hematol. 2002;41(3):317-325. https://doi.org/10.1016/S1040-8428(01)00143-3
  18. Kaltsatou A, Mameletzi D, Douka S. Physical and psychological benefits of a 24-week traditional dance program in breast cancer survivors. J Bodyw Mov Ther. 2011;15(2):162-167. https://doi.org/10.1016/j.jbmt.2010.03.002
  19. Kisner C, Colby LA. Therapeutic Exercise: Foundations and techniques. 4th ed. Philadelphia, PA, F.A. Davis Co., 2002;158.
  20. Krupp LB, LaRocca NG, Muir-Nash J, et al. The fatigue severity scale application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989;46(10):1121-1123. https://doi.org/10.1001/archneur.1989.00520460115022
  21. Lee MH. An effect of rhythmic movement therapy for adaptation state in mastectomy patients. Unpublished doctoral dissertation. Kyngpook National University, Taegu, Korea. 1995.
  22. MacVicar MG, Winningham ML, Nickel JL. Effects of aerobic interval training on cancer patients' functional capacity. Nurs Res. 1989;38(6):348-351.
  23. Markes M, Brockow T, Resch KL. Exercise for women receiving adjuvant therapy for breast cancer. Cochrane Database Syst Rev. 2006;(4):CD005001
  24. Mckenzie DC, Kalda AL. Effect of upper extremity exercise on secondary lymphedema in breast cancer patients: A pilot study. J Clin Oncol. 2003;21(3):463-466. https://doi.org/10.1200/JCO.2003.04.069
  25. Milne HM, Wallman KE, Gordon S, et al. Effects of a combined aerobic and resistance exercise program in breast cancer survivors: a randomized controlled trial. Breast Cancer Res Treat. 2008;108(2):279-288. https://doi.org/10.1007/s10549-007-9602-z
  26. Mock V, Dow KH, Meares CJ, et al. Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum. 1997;24(6):991-1000.
  27. Ogunleye AA, Holmes MD. Physical activity and breast cancer survival. Breast Cancer Res. 2009;11(5):106.
  28. Oldervoll LM, Ro M, Zwart JA, et al. Comparison of two physical exercise programs for the early intervention of pain in the neck, shoulders and lower back in female hospital staff. J Rehabil Med. 2001;33(4):156-161. https://doi.org/10.1080/16501970117295
  29. Partridge AH, Burstein HJ, Winer EP. Side effects of chemotherapy and combined chemohormonal therapy in women with early-stage breast cancer. J Natl Cancer Inst Monogr. 2002;(30):135-142.
  30. Pinto BM, Maruyama NC. Exercise in the rehabilitation of breast cancer survivors. Psychooncology. 1999;8(3):191-206. https://doi.org/10.1002/(SICI)1099-1611(199905/06)8:3<191::AID-PON355>3.0.CO;2-T
  31. Pollock ML, Wilmore JH, Fox SM. Health and Fitness Through Physical Activity, New York, John Wiley & Sons, 1978:301.
  32. Sandel SL, Judge JO, Landry N, et al. Dance and movement program improves quality-of-life measures in breast cancer survivors. Cancer Nurs. 2005;28(4):301-309.
  33. Sant M, Allemani C, Berrino F, et al. Breast carcinoma survival in europe and the united states. Cancer. 2004;100(4):715-722. https://doi.org/10.1002/cncr.20038
  34. Schwartz AL. Fatigue mediates the effects of exercise on quality of life. Qual Life Res. 1999;8(6):529-538. https://doi.org/10.1023/A:1008978611274
  35. Segar ML, Katch VL, Roth RS, et al. The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum. 1998;25(1):107-113.
  36. Senkus-Konefka E, Jassem J. Complications of breast cancer radiotherapy. Clin Oncol. 2006;18(3):229-235. https://doi.org/10.1016/j.clon.2005.11.004
  37. Shapiro CL, Recht A. Side effects of adjvant treatment of breast cancer. N Engl J med. 2001;344(26):1997-2008. https://doi.org/10.1056/NEJM200106283442607
  38. Shvartz E, Reibold RC. Aerobic fitness norms for males and females aged 6 to 75 years: A review. Aviat Space Environ Med. 1990;61(1):3-11.
  39. So WK, Marsh G, Ling WM, et al. The symptom cluster of fatigue, pain, anxiety and depression and the effect on the quality of life of women receiving treatment of breast cancer: A multicenter study. Oncol Nurs Forum. 2009;36(4):E205-E214. https://doi.org/10.1188/09.ONF.E205-E214
  40. Truong PT, Olivotto IA, Whelan TJ, et al. Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy. CMAJ. 2004;170(8):1263-1273. https://doi.org/10.1503/cmaj.1031000
  41. Windsor PM, Nicol KF, Potter J. A randomized controlled trial of aerobic exercise for treatment- related fatigue in men receiving radical external beam radiotherapy for localized prostate carcinoma. Cancer. 2004;101(1):550-557. https://doi.org/10.1002/cncr.20378
  42. Yoo YS. Effects of aquatic exercise program in the shoulder joint function immune response and emotional state in postmastectomy patients. J Catholic Med Col. 1996;49(2):806-823.
  43. Yun YH, Park Ys, Lee ES, et al. Validation of the Korean version of the EORTC QLQ-C30. Qual Life Res. 2004;13(4):863-868. https://doi.org/10.1023/B:QURE.0000021692.81214.70
  44. Zabora J, BrintzenhofeSzoc K, Curbow B, et al. The prevalence of psychological distress by cancer site. Psychooncology. 2001;10(1):19-28. https://doi.org/10.1002/1099-1611(200101/02)10:1<19::AID-PON501>3.0.CO;2-6

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