대한치과마취과학회지 (Journal of The Korean Dental Society of Anesthesiology)

  • 제12권2호
  • /
  • Pages.69-74
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  • 2012
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  • 1598-4044(pISSN)
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  • 2383-7039(eISSN)
대한치과마취과학회 (The Korean Dental Society of Anesthsiology)
권호 표지

임플란트 수술을 위한 미다졸람 정주와 아산화질소 흡입 병용 진정법의 효과와 안전성에 대한 전향적 무작위 대조군 연구

A Prospective, Randomized and Controlled Study for the Efficacy and Safety of Sedation Technique for Implant Surgery by Combining Nitrous Oxide and Intravenous Midazolam

  • 전승환 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 정신혜 (한양대학교 의과대학 치과학교실 치과보존과) ;
  • 김광수 (한양대학교 의과대학 치과학교실 예방치과) ;
  • 전상호 (고려대학교 안암병원 치과 구강악안면외과) ;
  • 황경균 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 박창주 (한양대학교 의과대학 치과학교실 구강악안면외과)
  • Jeon, Seung-Hwan (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Chung, Shin-Hye (Division of Conservative Dentistry, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Kim, Kwang-Soo (Division of Preventive Dentistry, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Jun, Sang-Ho (Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital, Korea University) ;
  • Hwang, Kyung-Gyun (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Park, Chang-Joo (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University)
  • 투고 : 2012.06.15
  • 심사 : 2012.07.02
  • 발행 : 2012.06.30
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초록

Background: The purpose of this study is to investigate the efficacy and safety of the sedation technique for implant surgery by combining the use of inhalation of nitrous oxide/oxygen with intravenous midazolam. Methods: Patients requiring surgery for the placement of dental implants were randomly allocated to two groups receiving intravenous midazolam or a combined technique using nitrous oxide/oxide and intravenous midazolam. Safety parameters, cooperation scores, anxiety scales, total amount of midazolam administered and recovery time were recorded and compared. Results: There were a statistically significant reduction in the amount of midazolam required to achieve optimal sedation (P<0.01), an overall significant reduction in recovery time (P<0.01), a significant reduction in anxiety scales (P<0.05), and a significant improvement in cooperation (P<0.05) and peripheral oxygen saturation (P<0.05) when a combined technique of inhalational $N_2O/O_2$ and midazolam was used. Conclusions: For implant surgery, this combining sedation technique could be safe and reliable, demonstrating reduction of total dose of midazolam and level of patient's anxiety and improvement in patient's recovery and cooperation.

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