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Musculoskeletal Models to Predict Patient-specific Gait Patterns Using Function-based Morphing Technique

기능기반 형상변형기술을 응용한 환자맞춤형 근골격 모델의 보행패턴 예측에 관한 연구

  • Received : 2012.08.09
  • Accepted : 2012.10.29
  • Published : 2012.12.01

Abstract

The configuration of a musculoskeletal (MS) system is closely related to the individual motions of the human body. Many researches have been focused on evaluating the associations between the MS configuration and the individual motion using patient-specific MS models, but it still remains a challenging issue to accurately predict the motion by differed configurations of the MS system. The main objective of this paper is to predict the changes of a patient-specific gait by altering the geometric parameters of the hip joint using function-based morphing method (FBM). FBM is suitable for motion analysis since this method provide a robust way to morph a MS model while preserving the biomechanical functions of the bones. Computed-muscle control technique is used to calculate the muscle excitations to reproduce the targeted motion within a digital MS model without the motion-captured data. We applied this approach to a patient who has an abnormal gait pattern. Results showed that the femoral neck length and the angle significantly affect to the motion especially for the hip abduction angle during gait, and that this approach is suitable for gait prediction.

Keywords

References

  1. Neumann, D.A. Kinesiology of the Musculoskeletal System: Foundations for Rehabilitation, Mosby Elsevier, pp. 28-45.
  2. Piazza, S.J., Okita, N. and Cavanagh, P.R. 2001, Accuracy of the Functional Method of Hipjoint Center Location, Journal of Biomechanics, 34, pp. 967-973. https://doi.org/10.1016/S0021-9290(01)00052-5
  3. Bartz, R.L., Noble, P.C., Kadakia, N.R. and Tullos, H.S. 2012, The Effect of Femoral Component in Artificial Hip Joint, The Journal of Bone and Joint Surgery, pp. 1300-1307.
  4. Lenaerts, G., De Groote, F., Demeulenaere, B., Mulier, M., Van der Perre, G., Spaepen, A. and Jonkers, I., 2008, Subject-specific Hip Geometry Affects Predicted Hip Joint Contact Forces During Gait, Journal of Biomechanics, 41, pp. 1243-1252. https://doi.org/10.1016/j.jbiomech.2008.01.014
  5. Arnold, A.S., Blemker, S.S. and Delp, S.L. 2001, Evaluation of a Deformable Musculoskeletal Model for Estimating Muscle-Tendon Lengths During Crouch Gait. Annals of Biomedical Engineering, 29, pp. 263-274. https://doi.org/10.1114/1.1355277
  6. Carter, D.R., van der Meulen, M.C.H. and Beaupre, G.S., 2001, Mechanical Factors in Bone Growth and Development. BONE, pp. 1-6.
  7. Arnold, A.S. and Delp, S.L., 2001, Rotational Moment Arms of the Medial Hamstrings and Adductors Vary with Femoral Geometry and Limb Position: Implications for the Treatment of Internally Rotated Gait, Journal of Biomechanics, pp. 1-11.
  8. Pennestri, E., Stefanelli, R., Valentini, P.P. and Vita, L., 2007, Virtual Musculo-skeletal Model for the Biomechanical Analysis of the Upper Limb, Journal of Biomechanics, 40(6), pp. 1350-1361. https://doi.org/10.1016/j.jbiomech.2006.05.013
  9. Delp, S.L. and Loan, J.P., 1995, A Graphicbased Software System to Develop and Analyze Models of Musculoskeletal Structures, Computers in Biology and Medicine, pp. 21-34.
  10. Delp, S.L., Anderson, F.C., Arnold, A.S., Loan, P., Habib, A., John, C.T., Guendelman, E., et al., 2007. OpenSim: Open-Source Software to Create andAnalyze Dynamic Simulations of Movement, IEEE Transactions on Biomedical Engineering, 54, pp. 1940-1950. https://doi.org/10.1109/TBME.2007.901024
  11. Blemker, S.S., Asakawa, D.S., Gold, G.E. and Delp, S.L., 2007, Image-Based Musculoskeletal Modeling- Applications, Advances, and Future Opportunities. Journal of Magnetic Resonance Imaging, 25, pp. 441-451. doi:10.1002/jmri.20805
  12. Scheys, L., Desloovere, K., Suetens, P. and Jonkers, I., 2011, Level of Subject-specific Detail in Musculoskeletal Models Affects Hip Moment Arm Length Calculation During Gait in Pediatric Subjects with Increased Femoral Anteversion. Journal of Biomechanics, 44(7), pp. 1346-1353. https://doi.org/10.1016/j.jbiomech.2011.01.001
  13. Lenaerts, G., De Groote, F., Demeulenaere, B., Mulier, M., Van der Perre, G., Spaepen, A. and Jonkers, I., 2008, Subject-specific Hip Geometry Affects Predicted Hip Joint Contact Forces During Gait, Journal of Biomechanics, 41, pp. 1243-1252. https://doi.org/10.1016/j.jbiomech.2008.01.014
  14. Rajamani, K.T., Hug, J., Nolte, L.-P. and Styner, M., 2004, Bone Morphing with Statistical Shape Models for Enhanced Visualization, In: Proceedings of SPIE Medical Imaging (Vol. 5367, pp. 122-130). Presented at the In: Proceedings of SPIE Medical Imaging, SPIE.
  15. Rajamani, K.T., Styner, M.A., Talib, H., Zheng, G., Nolte, L.P. and Ballester, M.A.G., 2007, Statistical Deformable Bone Models for Robust 3D Surface Extrapolation from Sparse Data, Medical Image Analysis, 11(2), pp. 99-109. https://doi.org/10.1016/j.media.2006.05.001
  16. Park, B.K., Chae, J.W. and Kim, J.J., 2011, Parametric Morphing of Subject-specific NURBS Models for Human Proximal Femurs Subject to Femoral Functions, Transactions of the Society of CAD/CAM Engineers, 16(6), pp. 458-466.
  17. Delp, S.L., Loan, J.P., Hoy, M.G., Zajac, F.E., Topp, E.L. and Rosen, J.M., 1990, An Interactive Graphics-based Model of the Lower Extremity to Study Orthopaedic Surgical Procedures. IEEE Transactions on Biomedical Engineering 37, pp. 757-767. https://doi.org/10.1109/10.102791
  18. Sciavicco, L., Siciliano, B., 1996, Modelling and Control of Robot Manipulators. Second Edition, London: Springer-Verlag. pp. 166-191.
  19. Delp, S.L., 1990, Surgery Simulation: A Computer Graphics System to Analyze and Design Musculoskeletal Reconstructions of the Lower Limb, Ph.D. dissertation, Stanford University.
  20. Zajac, F.E., 1989, Muscle and Tendon: Properties, Models, Scaling and Application to Biomechanics and Motor Control, CRC Critical Reviews in Biomedical Engineering 17, pp. 359-411.
  21. Thelen, D.G. and Anderson, F.C., 2006, Using Computed Muscle Control to Generate Forward Dynamic Simulations of Human Walking from Experimental Data, Journal of Biomechanics, 39, pp. 1107-1115. https://doi.org/10.1016/j.jbiomech.2005.02.010
  22. Jun, Y.T. and Choi, K., 2010, Design of Patientspecic Hip Implants Based on the 3D Geometry of the Human Femur, Advances in Engineering Software, 41, pp. 537-547. https://doi.org/10.1016/j.advengsoft.2009.10.016
  23. Andersen, M.S., Damsgaard, M. and Rasmussen, J., 2009, Kinematic Analysis of Over-determinate Biomechanical Systems, Computer Methods in Biomechanics and Biomedical Engineering, 12(4), pp. 371-384. https://doi.org/10.1080/10255840802459412