Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Preparation of New Binaphthol Derived Chiral Stationary Phases

  • Zhang, Yi Jun (Department of Chemistry, Graduate School, Kyungpook National University) ;
  • Ryoo, Jae-Jeong (Department of Chemistry, Graduate School, Kyungpook National University)
  • Received : 2011.05.12
  • Accepted : 2011.07.06
  • Published : 2011.08.20
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Abstract

To develop more advanced binaphthol derived CSPs, two new 1,1-bi-2-naphthol derived chiral stationary phases (CSPs) (CSP 1 and CSP 2) were prepared by connecting with silica gel at a hydroxy (OH) group of binaphthol. Previously reported two 1,1'-binaphthyl-2,2'-diamine derived CSPs (CSP 3 and CSP 4) were also prepared to compare the role of their functional groups (-OH and -$NH_2$) with CSP 1 and CSP 2. Enantioseparation of randomly selected, 11 chiral compounds on these four CSPs was performed and the results compared to each other. 3,5-Dinitrobenzoyl (3,5-DNB) derivatives of each CSP showed better results than the others and binaphthyldiamine derived CSP showed slightly better than binaphthol derived one.

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References

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