Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

The Promoting Effect of Cornus officinalis fermented with Lactobacillus rhamnosus on Hair Growth

산수유 유산균 발효액의 모발성장 효과

  • Park, Jang-Soon (Department of Beauty Science, Kwangju Women's University) ;
  • Lee, Jae-Sug (Department of Beauty Science, Kwangju Women's University)
  • 박장순 (광주여자대학교 미용과학과) ;
  • 이재숙 (광주여자대학교 미용과학과)
  • Received : 2011.06.13
  • Accepted : 2011.08.25
  • Published : 2011.09.30
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Abstract

The bacterial growth and pH of Cornus officinalis fermented with Lactobacillus rhamnosus during fermentation were evaluated. As the results, the number of the fermentation after fermentation always remained higher than 6 log CFU/mL and the pH of those ranged from 4 to 6. To evaluate the effect of Cornus officinalis fermented with Lactobacillus rhamnosus on hair growth promotion in C57BL/6 mice, Six weeks old male mice were divided into four groups including normal group (saline), negative control group (essence base), positive control group (minoxidil) and experimental group (Cornus officinalis and animal milk fermented with Lactobacillus rhamnosus mixed in negative control). And they were applied topically with test materials for 8 days. Hair regrowth effect in experimental group using gross and histological examination was higher than that in positive control group. Body weight and food intake of four groups didn't show significant difference. These results indicated that the Cornus officinalis fermented with Lactobacillus rhamnosus can be used practically for hair growth or prevention of hair loss.

Keywords

References

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