핵의학기술 (The Korean Journal of Nuclear Medicine Technology)
- 제15권1호
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- Pages.101-105
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- 2011
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- 1229-9901(pISSN)
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- 2982-8406(eISSN)
제조회사에 따른 Estradiol 결과값의 비교
Comparison of Estradiol Results according to Manufacturer
- 김대운 (서울대학교병원 핵의학과) ;
- 신희정 (서울대학교병원 핵의학과) ;
- 유태민 (서울대학교병원 핵의학과) ;
- 노경운 (서울대학교병원 핵의학과) ;
- 김현주 (서울대학교병원 핵의학과)
- Kim, Dae-Woon (Department of Nuclear Medicine, Seoul National University Hospital) ;
- Shin, Hee-Jung (Department of Nuclear Medicine, Seoul National University Hospital) ;
- You, Tae-Min (Department of Nuclear Medicine, Seoul National University Hospital) ;
- Noh, Gyeong-Woon (Department of Nuclear Medicine, Seoul National University Hospital) ;
- Kim, Hyun-Joo (Department of Nuclear Medicine, Seoul National University Hospital)
- 발행 : 2011.04.30
초록
목적 : Estradiol은 월경주기와 배란유도에 중요한 검사로 현재 전국의 핵의학 검사실에서 일반환자와 불임환자를 대상으로 검사가 시행되고 있으며 폐경은 진단하는데 난포자극호르몬(FSH)와 황체형성호르몬(LH)와 함께 중요한 검사이다. 전국 병원 중 핵의학 검체검사 외부정도관리에 참여하고 있는 기관은 70개 중에서 해당 검사를 측정하는 병원이 37개이며 이중 20개의 병원 즉 54%가 A사의 kit를 사용하고 있다. 이 중 A사 Kit의 검사 결과가 다른 kit와 다르게 높게 보고되어 이 현상에 대한 문제점을 파악하며, 더불어 폐경여성의 호르몬 치료에서 각 호르몬제를 복용했을 때, 이에 대한 영향을 알아보고자 한다. 실험재료 및 방법 : 2010년 4월부터 8월까지 본원에 의뢰된 Estradiol 검체 중 검사 결과가 약 100 pg/ml 이상인 75개의 검체를 대상으로 방사면역측정법(RIA) 검사인 A사 B사 C사 D사의 Kit와 화학발광측정법(CMIA)으로 검사를 하여 결과를 비교 하였다. 결과 : 각각의 제조회사의 Kit로 측정된 결과 갑의 평균값을 이용하여 구한 상관계수(
Purpose: Estradiol in the menstrual cycle and ovulation induction as an important test of currently national nuclear medicine laboratory in the normal patients and patients with infertility tests are being performed. For the diagnosis of menopause is an important test with follicle stimulating hormone (FSH) and Luteinizing hormone (LH). Currently participating in external quality control of the nation's hospitals that is 54 percent of 37 hospitals, 20 hospitals have been using A's reagent. The kit's test results are highly different from other kit comes with the test results of specimens have been found. And for the phenomenon is to study the problem. Materials and Methods: Estraiol test were referred to our hospital which results of samples as more than 100pg/ml 75 specimens measured by radioimmunoassay(RIA) test with company A company B company C company D Kit, Chemiluminescent assay (CMIA) to examine and compare to the results from april to August in 2010. Results: Kit for each manufacturing company as measured by the results obtained using the average value of the correlation coefficient (R2) and A company 0.8906 B 0.9527 C 0.9547 and D company correlation coefficient of 0.873 showed a good correlation that measuring the results of A company high concentrations when Company B Company C Company D with CMIA test concentrations measured low results that the two cases were discovered specimens. Conclusion: Most of the test results of 75 samples came up with a similar trend, but two cases were reported in the patients very differently. A company result reported higher than 700 pg/ml, while the rest of other test results report was approximately 10 pg/ml. The common point of two samples more than 50 years patients are estimated to be diagnosed with cancer in postmenopausal patients receiving treatment and levels of FSH were found to be greater than 50 mIU/ml. Did not identify the exact cause. I suggest if you are using A company kit that need to again check when Estradiol result and follicle stimulating hormone results is higher.