Transactions of the Korean Society of Mechanical Engineers B (대한기계학회논문집B)

The Korean Society of Mechanical Engineers (대한기계학회)
권호 표지
DOI QR코드

DOI QR Code

Analysis of the Bioheat Equation Considering Tissue Layers with Sinusoidal Temperature Oscillation on the Skin

사인 주기의 온도 변화가 가해지는 피부 조직의 생체열 방정식에 대한 해석

  • Choi, Woo-Lim (Dept. of Mechanical Design Engineering, Chonbuk Nat'l Univ.) ;
  • Moon, Sang-Don (Dept. of Mechanical Design Engineering, Chonbuk Nat'l Univ.) ;
  • Youn, Suk-Bum (Dept. of Mechanical Design Engineering, Chonbuk Nat'l Univ.) ;
  • Im, Ik-Tae (Dept. of Mechanical Design Engineering, Chonbuk Nat'l Univ.)
  • 최우림 (전북대학교 기계설계공학부) ;
  • 문상돈 (전북대학교 기계설계공학부) ;
  • 윤석범 (전북대학교 기계설계공학부) ;
  • 임익태 (전북대학교 기계설계공학부)
  • Received : 2010.07.06
  • Accepted : 2011.05.19
  • Published : 2011.08.01
Download PDF
⟨ Previous Next ⟩

Abstract

We investigate the transient temperature response in biological tissue whose surface is exposed to alternately varying sinusoidal oscillation. Based on the Pennes bio-heat equation, we apply numerical analysis using a finite element method to find the effects of the physical properties of the skin layers. Three layers of tissue-epidermis, dermis, and subcutaneous-are considered as the solution region. We investigate the effects of different properties of the skin layers on the temperature profile. We also investigate the effects of the perfusion rate for the dermis, which is the most sensitive layer. The results show that the temperature profile of tissue depth has a discontinuous point when different physical properties are used.

본 연구에서는 표면에 사인주기의 온도변화를 주었을 때 인체피부 조직의 온도변화에 대해 연구 하였다. 표피, 진피 및 피하조직으로 이루어진 피부 각 층의 서로 다른 물성치의 영향을 Pennes 열전달 방정식을 이용한 수치해석방법으로 풀이하여 조사하였다. 각 조직의 서로 다른 물성치가 온도분포에 미치는 영향에 대해 조사하였다. 또 물성치 변화의 영향을 많이 받는 진피부분에 대해서 관류율의 영향을 조사하였다. 해석 결과 동일한 물성치를 사용한 경우와 달리 서로 다른 물성치를 사용하였을 때, 피부깊이에 따른 온도분포가 불연속적으로 나타났다.

Keywords

References

  1. Yoo, J. H., Park, D. K., Yang, S. W., Park, M., Chu, S. S. and Lee, S. B., 1986, "A Study on the RF and Microwave Hyperthermia System for Cancer Therapy," Proceeding of the IEEK, Vol. 9, No. 1, pp. 348-351.
  2. Hong, S. H., Lee, S. W., Jang, J. S., Choi, S. G., Kim, P. H., Jang, W. S., Choi, E. H., Koo, K., Huh, K., Kang, D. C., Han, D. H. and Jang, H. W., 1987, "A Study on Hyperthermia Apparatus for Cancer," KOSEF Report.
  3. Zaidi, A. K., Patil, M. S., Bagewadikar, R. S., Subramanian, M. and Kaklij, G. S., 2002, "Radioprotection by Whole Body Hyperthermia: Possible Mechanism(s)," Journal of Thermal Biology, Vol. 27, pp. 29-37. https://doi.org/10.1016/S0306-4565(01)00012-2
  4. Incropera, F. P., DeWitt, D. P., Bergman, T. L. and Lavine, A. S., 2007, Introduction to Heat Transfer, John Wiley & Sons Inc, Hoboken, 5th edition.
  5. Arkin, H., Xu, L. X. and Holmes, K. R., 1994, "Recent Developments in Modeling Heat Transfer in Blood Perfused Tissues," IEEE Transactions on Biomedical Engineering, Vol. 41, No. 2. https://doi.org/10.1109/10.284920
  6. Yuan, P., Liu, H. E., Chen, C. W. and Kou, H. S., 2008, "Temperature Response in Biological Tissue by Alternating Heating and Cooling Modalities with Sinusoidal Temperature Oscillation on the Skin," International Communications in Heat and Mass Transfer, Vol. 35, pp. 1091-1096. https://doi.org/10.1016/j.icheatmasstransfer.2008.05.012
  7. Liu, J. and Xu, L. X., 1999, "Estimation of Blood Perfusion using Phase Shift in Temperature Response to Sinusoidal Heating at the Skin Surface," IEEE Transactions on Biomedical Engineering, Vol. 46, No. 9, pp. 1037-1043. https://doi.org/10.1109/10.784134
  8. Shih, T. C., Yuan, P., Lin, W. L. and Kou, H. S., 2007, "Analytical Analysis of the Pennes Bioheat Transfer Equation with Sinusoidal Heat Flux Condition on Skin Surface," Medical Engineering & Physics, Vol. 29, pp. 946-953. https://doi.org/10.1016/j.medengphy.2006.10.008
  9. Jaunich, M., Raje, S., Kim, K. H., Mitra, K. and Guo, Z., 2008, "Bio-Heat Transfer Analysis during Short Pulse Laser Irradiation of Tissues," International Journal of Heat and Mass Transfer, Vol. 51, pp. 5511-5521. https://doi.org/10.1016/j.ijheatmasstransfer.2008.04.033
  10. Southwood, W. F. W., 1955, "The Thickness of the Skin," Plast Reconstr Surg, Vol. 15, pp. 423-429. https://doi.org/10.1097/00006534-195505000-00006
  11. Artz, C. P., Moncrief, J. A., Pruitt, B. A. Jr., 1979, Burns: a Team Approach, Saunders, Philadelphia, pp. 24-44.
  12. Torvi, D. A. and Dale, J. D., 1994, "A Finite Element Model of Skin Subjected to a Flash Fire," ASME J Biomech. Eng., Vol. 116, pp. 250-255 https://doi.org/10.1115/1.2895727

Cited by

  1. Numerical Study on the Temperature Profiles and Degree of Burns in Human Skin Tissue During Combined Thermal Therapy vol.67, pp.9, 2015, https://doi.org/10.1080/10407782.2014.955338