Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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The comparison of pathogenicity in the SPF chickens challenged with avian reovirus and/or fowl adenovirus

SPF 닭에서 레오바이러스와 아데노바이러스의 단일 혹은 혼합감염에 따른 병원성 비교

  • Min, Kyeong-Cheol (College of Veterinary Medicine, Chungbuk National University) ;
  • Choi, Dong-Myong (College of Veterinary Medicine, Chungbuk National University) ;
  • Kim, Ji-Yea (College of Veterinary Medicine, Chungbuk National University) ;
  • Jeon, Eun-Ok (College of Veterinary Medicine, Chungbuk National University) ;
  • Byun, Sung-Hwan (College of Veterinary Medicine, Chungbuk National University) ;
  • Mo, In-Pil (College of Veterinary Medicine, Chungbuk National University)
  • 민경철 (충북대학교 수의과대학 조류질병학실험실) ;
  • 최동명 (충북대학교 수의과대학 조류질병학실험실) ;
  • 김지예 (충북대학교 수의과대학 조류질병학실험실) ;
  • 전은옥 (충북대학교 수의과대학 조류질병학실험실) ;
  • 변성환 (충북대학교 수의과대학 조류질병학실험실) ;
  • 모인필 (충북대학교 수의과대학 조류질병학실험실)
  • Received : 2011.03.25
  • Accepted : 2011.04.20
  • Published : 2011.06.30
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Abstract

Avian reovirus (ARV) and fowl adenovirus (FAdV) were evaluated for pathogenicity in specific pathogen free (SPF) chickens. ARV was isolated from the broilers with history of malabsorption syndrome (MAS). FAdV was isolated from the layer breeders with inclusion body hepatitis and hydropericardium syndrome. Total 6 inoculated groups including 1 un-inoculated group were organized and inoculated with the ARV and/or FAdV by oral route. The minimal pathological lesions and lower viral gene detection rates were present in the ARV inoculated groups compared to those of FAdV or ARV/FAdV inoculated groups. Common gross lesions in the ARV inoculated group were distended intestine with foamy contents and in the FAdV group there were foamy cecal contents and hydropericardium among the evaluation methods such as gross and histological lesion, viral gene detection, body weight and serum chemistry, histopathological lesion score was reliable especially in the liver lesions such as hepatic necrosis and lymphocytic infiltration. However, we did not success to evaluate the synergetic effect of mixed infection of ARV and FAdV in this study. Therefore, we need further study to reproduce malabsorption syndrome of ARV infection using different viral agent such as rotavirus and using different dose of virus.

Keywords

References

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