한약처방의 표준화를 위한 HPTLC의 활용

The Application of High Performance Thin Layer Chromatography for Herbal Formula Standardization

  • 최민경 (대전대학교 한의과대학 간장면역학교실) ;
  • 김형극 (대전대학교 한의과대학 간장면역학교실) ;
  • 왕경화 (대전대학교 한의과대학 간장면역학교실) ;
  • 손창규 (대전대학교 한의과대학 간장면역학교실)
  • Choi, Min-Kyung (Liver & Immunology Research Center, Oriental hospital of Daejeon University) ;
  • Kim, Hyeong-Geug (Liver & Immunology Research Center, Oriental hospital of Daejeon University) ;
  • Wang, Jing-Hua (Liver & Immunology Research Center, Oriental hospital of Daejeon University) ;
  • Son, Chang-Gue (Liver & Immunology Research Center, Oriental hospital of Daejeon University)
  • 투고 : 2011.04.25
  • 심사 : 2011.07.13
  • 발행 : 2011.07.30

초록

Objective: The purpose of this study is to expatiate on high performance thin layer chromatography (HPTLC) as a simple, easy and scientific method for evaluation and standardization of herbal formulae. Methods: Through retrieving HPTLC application for herbal formulae in the literatures, the current situation of HPTLC application, and potential as well as limitation of HPTLC as a standardization method for multi-herbal drug was studied. Results: HPTLC is a speedy, inexpensive and well-operable tool for possessing multi-capability on component identification, separation, quantification and purification compared to other methods, such as high performance liquid chromatography (HPLC), gas chromatography (GC). Conclusions: HPTLC is considered as an available and convenient method for quality control and standardization of multi-herbal drugs. Thereby, this method could be recommended to widely applicate in the traditional Korean medicine.

키워드

참고문헌

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