한국축산식품학회지 (Food Science of Animal Resources)

  • 제31권3호
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  • Pages.442-450
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  • 2011
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  • 2636-0772(pISSN)
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  • 2636-0780(eISSN)
한국축산식품학회 (Korean Society for Food Science of Animal Resources)
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실험동물에서 기능성 요구르트(R&B Rhythm®)의 변비개선효과

Effect of Functional Yogurt (R&B Rhythm®) on the Improvement of Constipation in Animal Models

  • 임중현 (중앙대학교 동물자원과학과) ;
  • 최재경 (중앙대학교 동물자원과학과) ;
  • 이명희 ((주)한국야쿠르트 중앙연구소) ;
  • 안영태 ((주)한국야쿠르트 중앙연구소) ;
  • 이정희 ((주)한국야쿠르트 중앙연구소) ;
  • 허철성 ((주)한국야쿠르트 중앙연구소) ;
  • 김근배 (중앙대학교 동물자원과학과)
  • Im, Joong-Hyun (Department of Animal Science and Technology, Chung-Ang University) ;
  • Choi, Jae-Kyoung (Department of Animal Science and Technology, Chung-Ang University) ;
  • Lee, Myoung-Hee (Research and Business Development Center, Korea Yakult Co., Ltd.) ;
  • Ahn, Young-Tae (Research and Business Development Center, Korea Yakult Co., Ltd.) ;
  • Lee, Jung-Hee (Research and Business Development Center, Korea Yakult Co., Ltd.) ;
  • Huh, Chul-Sung (Research and Business Development Center, Korea Yakult Co., Ltd.) ;
  • Kim, Geun-Bae (Department of Animal Science and Technology, Chung-Ang University)
  • 투고 : 2011.04.22
  • 심사 : 2011.06.08
  • 발행 : 2011.06.30
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초록

본 연구는 mouse와 rat에 대한 발효유의 급여에 의한 장 기능 개선과 변비 예방 효과 및 변비 치료 효과를 알아보고자 수행하였다. 동물실험을 통하여 발효유의 투여 농도에 따라 유의적인 차이를 확인할 수 있었으며, 소화관 이 실험에서는 중농도와 고농도 투여에서 유의적인 수준으로 이동률의 증가가 관찰되었고, 변비 예방 및 치료 효과에 대한 실험에서는 변비 유발 물질인 loperamide 단독 투여군에 비하여 발효유를 함께 투여한 결과, 변의 개수는 고농도 투여에 의하여 유의적인 증가가 관찰되었고, 분변량과 변의 수분함량은 중농도와 고농도 투여군에서 유의적인 증가가 관찰되었다. 이상의 동물 실험 결과를 통하여, 기능성 발효유의 반복적인 투여는 변비 예방과 변비 치료에 효과가 있는 것으로 확인되었다.

We investigated the improvement in intestinal function and the constipation preventive and remedial effects of the fermented milk product R&B $Rhythm^{(R)}$ in mice and rats. The results showed that the effects varied significantly among different doses. The digestive tract transfer rate increased dramatically in a dose-dependent manner in both animals. Compared with treating constipation with loperamide alone, treatment with loperamide and the fermented milk R&B Rhythm improved the number of fecal pellets from the animals, suggesting that it is effective for preventing and relieving constipation. Both the quantity of feces and water content of the feces increased significantly at high levels of yogurt feeding. These results suggest that repetitively ingesting fermented milk products could be effective for preventing and treating constipation symptoms.

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피인용 문헌

  1. Effects of Dietary Fiber Isolated from Synurus deltoides on Constipation in Loperamide-Induced Rats vol.40, pp.12, 2011, https://doi.org/10.3746/jkfn.2011.40.12.1715
  2. Quality Properties of Yogurt Added with Hot Water Concentrates from Allium hookeri Root vol.43, pp.9, 2014, https://doi.org/10.3746/jkfn.2014.43.9.1415
  3. Effect of Lactic Acid Bacteria-Fermented Mulberry Leaf Extract on the Improvement of Intestinal Function in Rats vol.37, pp.4, 2017, https://doi.org/10.5851/kosfa.2017.37.4.561
  4. 송기 분말이 Loperamide로 유도된 흰쥐의 변비 완화에 미치는 효과 vol.27, pp.5, 2011, https://doi.org/10.17495/easdl.2017.10.27.5.548