Journal of the Korean Academy of Clinical Electrophysiology (대한임상전기생리학회지)

The Korean Academy of Clinical Electrophysiology (대한임상전기생리학회)
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The Change of Image and Organization after MicroCurrent Stimulation in Osteoarthritis in Rat

뼈관절염이 유발된 흰쥐에 미세전류자극 적용이 영상 및 조직학적 변화에 미치는 영향

  • Jin, Hee-Kyung (Department of Physical Therapy, Graduate School, Seonam University) ;
  • Kim, Young-Nam (Department of Physical Therapy, Nambu University) ;
  • Cho, Woon-Su (Department of Physical Therapy, Nambu University) ;
  • Hwang, Tae-Yeon (Department of Physical Therapy, Chunnam Techno College) ;
  • Park, Jang-Sung (Department of Physical Therapy, Seonam University)
  • 진희경 (서남대학교 대학원 물리치료학과) ;
  • 김용남 (남부대학교 물리치료학과) ;
  • 조운수 (남부대학교 물리치료학과) ;
  • 황태연 (전남과학대학 물리치료과) ;
  • 박장성 (서남대학교 물리치료학과)
  • Received : 2011.04.04
  • Accepted : 2001.05.17
  • Published : 2011.06.30
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Abstract

Purpose : This study investigated the effects of osteoarthritis therapy using images and histological diagnosis after microcurrents were applied to osteoarthritic rats. Methods : Osteoarthritis was induced with a mixture of 2% carrageenan and 2% kaolin. The mixture (0.1 $m{\ell}$) was injected into the knee joints of rats. Osteoarthritis with articulation received microcurrent stimulation for four weeks (15 min/day, 5 days/week): treated with pulsation frequency of 5 pps and a stimulation intensity of 25 ${\mu}A$. Results : Osteoarthritis of the control group constantly changed. The group with a stimulation intensity of 25 ${\mu}A$ applied to the surface of the articular cartilage experienced near normal recovery according to image diagnosis. The result of histological and immunohistochemistry inspection confirms that microcurrent stimulation had a positive effect on the treatment of osteoarthritis. Conclusion : The differences among images and histological diagnoses show that steoarthritis will experience constant progression from stimulation.

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References

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