DOI QR코드

DOI QR Code

Literature Review on Safety of Pharmacopuncture according to Sasang Constitutional Medicine

동의수세보원(東醫壽世保元) 신정(新定) 처방(處方) 약재(藥材)의 약침 안전성 문헌 조사

  • Oh, Seung-Yun (Dept. of Constitutional Medicine, College of Oriental Medicine, Wonkwang Univ.) ;
  • Kim, Koo (Dept. of Constitutional Medicine, College of Oriental Medicine, Wonkwang Univ.) ;
  • Kwon, Young-Mi (Dept. of Constitutional Medicine, College of Oriental Medicine, Wonkwang Univ.) ;
  • Lee, Si-Woo (Korea Institute of Oriental Medicine) ;
  • Jang, Eun-Su (Korea Institute of Oriental Medicine) ;
  • Joo, Jong-Cheon (Dept. of Constitutional Medicine, College of Oriental Medicine, Wonkwang Univ.)
  • 오승윤 (원광대학교 한의과대학 사상체질과) ;
  • 김구 (원광대학교 한의과대학 사상체질과) ;
  • 권영미 (원광대학교 한의과대학 사상체질과) ;
  • 이시우 (한국한의학연구원) ;
  • 장은수 (한국한의학연구원) ;
  • 주종천 (원광대학교 한의과대학 사상체질과)
  • Received : 2010.08.13
  • Accepted : 2010.09.01
  • Published : 2011.03.31

Abstract

1. Objectives: Pharmacopuncture according to Sasang Constitutional Medicine is new field of constitutional medicine. We investigated safety of pharmacopunctures to develop this treatment. 2. Methods: We searched for papers in fifteen Korean oriental medical journals and four online searching portal articles. Hepatotoxicity, nephrotoxicity and general toxicity tests were investigated about one hundred thirty kinds of pharmacopunctures. 3. Results: Toxicity test about 36 kinds of 130 pharmacopunctures were investigated. 1) Hepatotoxicity and nephrotoxicity test of pharmacopunctures were searched in 11 of 38 Soeumin herbs, 8 of 36 Soyangin herbs, 5 of 44 Taeeumin herbs and 1 of 12 Taeyangin herbs. From among these herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Fructus alpiniae oxyphyllae(益智仁), Semen crotonis(巴豆), Radix bupleuri(柴胡) and Semen armeniacae amarum(杏仁) pharmacopunctures. 2) General toxicity test of pharmacopunctures were searched in 8 of 38 Soeumin herbs, 9 of 36 Soyangin herbs, 6 of 44 Taeeumin herbs and 2 of 12 Taeyangin herbs. from among thes herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Radix ginseng(人蔘), Semen crotonis(巴豆), Rhizoma seu radix notopterygii(羌活), Radix aralia cordatae(獨活), Semen armeniacae amarum(杏仁) and Radix scutellariae(黃芩) and Cortex acanthopanacis(五加皮) pharmacopunctures. 4. Conclusions: From these results, we must decide extraction method, concentration and dose carefully to use the toxic pharmacopuncture. More toxicity test and further study is needed about pharmacopuncture treatment in Sasang Constitutional Medicine.

Keywords

References

  1. Kim JH, Song JM. A Study on the Acupoints in the view of Sasang Constitutional Medicine - based on 'Chimgugabulgyung(鍼灸甲乙經)'-. J Sasang Constitut Med. 2005;17(3):31-54.(Korean)
  2. Cho HS. Approach in Selecting Four Constitutional Acupuncture. J Sasang Constitut Med. 2005;17(1):1-15.(Korean)
  3. Han KS, Park SS A literature study on the treatment of acupuncture for the constituution - through the study for the detail of 'Hwangjenaikyung'(黃帝內經)-. J Sasang Constitut Med. 2001;13(3):8-14.(Korean)
  4. 전국한의과대학 침구경혈학교실. 침구학. 서울:집문당. 1991:1457.
  5. 대한약침학회 학술위원회. 약침학. 서울:엘스비어코리아. 2008:6-8.
  6. 남현석. 태음인의 우황약침. 서울:대한약침학회지. 2001;4(3):105-8.
  7. Joo JC. Lee SW. Basis of pharmacopuncture according to Sasang Constitutions. The 15th international congress of oriental medicine. 2010;15:103.(Korean)
  8. Jun KS, Nam SS, Lee JD, Choi DY, Ahn BC, Park DS, Lee YH, Choi YT.A study of clinical trial method for safety of herb-acupuncture. J of Korean acupuncture & moxibustion society. 1998;15(2):183-98.(Korean)
  9. Lee JY, Han YJ, Kim JH, Kim YJ, Kwon KR. Type analysis of pharmacopuncture papers published in the journal of Korean institute of pharmacopuncture. J of Korean institute of pharmacopuncture. 2006;9(3):147-54. (Korean) https://doi.org/10.3831/KPI.2006.9.3.147
  10. Lee JE, Nam SS, Lee JD, Choi DY, Ahn BC, Park DS, Lee YH, Choi YT. The analysis on the 8 aqua-acupuncture's stability. J of Korean acupuncture & moxibustion society. 1999;16(1):24.(Korean)
  11. Yoo HS, Lee YY, Cho JH, Lee YW, Son CG, Cho CK, Hwang KJ. A Study on recent tendency of anti-tumor herbal acupuncture. J of Korean institute of pharmacopuncture. 2001;4(3):23-27.(Korean) https://doi.org/10.3831/KPI.2001.4.3.023
  12. Yoo HS, Bang SH, Cho CK. A recent study of anti-tumor herbal acupuncture in Korea. J of Korean institute of pharmacopuncture. 2006;9(3):79-88.(Korean) https://doi.org/10.3831/KPI.2006.9.3.079
  13. Bang SH, Kwon KR, Yoo HS. Two cases of non-small cell lung cancer treated with intravenous cultivated Wild Ginseng pharmacopuncture. J of Korean institute of pharmacopuncture. 2008;11(2):13-19.(Korean) https://doi.org/10.3831/KPI.2008.11.2.013
  14. Cho BJ, Kwon KR.Effects of cultivated Wild Ginseng herbal acupuncture to the serum cytokine on hepatic metastatic model using Colon26-L5 carcinoma cells. J of Korean institute of pharmacopuncture. 2006;9(1): 127-37.(Korean) https://doi.org/10.3831/KPI.2006.9.1.127
  15. Kwon KR, Yoon HC, Kim HH. Anti-cancer effects of cultivated Wild Ginseng herbal acupuncture in C57BL/6 mice injected with B16/F10 cells and reproductive toxicity by Doxorubicin. J of Korean acupuncture & moxibustion society. 2006;23(1):105-20. (Korean)
  16. 김창민, 신민교, 안덕균, 이경순, 강병수, 강상수, et al. 중약대사전. 도서출판 정담, 서울, 1997: 102-7, 1056-64, 2622-33, 3017-22, 3473-91, 3460-3, 4141-9, 4478-87, 5001-9.
  17. Liu CT, Chuang PT, Wu CY, Weng YM, Chen W, Tseng CY. Antioxidative and in vitro hepatoprotective activity of Bupleurum kaoi leaf infusion. Phytother Res. 2006;20(11):1003-8. https://doi.org/10.1002/ptr.1946
  18. Shim BS, Park JK, Choi SH. Study on toxicity, anti- cancer and NK cell activity of Laetril oil. J of Korean oriental oncology 2000;6(1):19-28.(Korean)
  19. Liang AH, Nie SQ, Xue BY, Li GQ, Li ZL. Effects of processing on special toxicity and pharmacodynamics in semen Armeniacae amarum. Zhongguo Zhong Yao Za Zhi. 1993;18(8):474-8, 509.
  20. Kim YK, Lee JH, Song KY, Park SK, Kim CS. Studies on the liver toxicities with different dosage of wild Aconiti tuber decoction. The Korean Journal of Oriental Medical Prescription. 2005;13(1):123-43.(Korean)
  21. Kang SK, Lee HJ. A study on the safe utilization and standardization of Ginseng radix aqua-acupuncture solution by three manufacturing methods. J Korean Oriental Med. 1994;15(1):282-305.(Korean)
  22. Koh BS, Joo HJ, Ma JY, Park KJ, Ahn SW. Studies on manufacture system of Hwanggum(黃芩) aqua-acupuncture by boiling water method. J of Korean institute of pharmacopuncture. 1997;1(1):77-86.(Korean) https://doi.org/10.3831/KPI.1997.1.1.077