수 차례 국소 재발한 피부 점액성 에크린 암

A Case of Multiple Recurred Mucinous Eccrine Carcinoma

  • 이윤정 (경상대학교 의학전문대학원 성형외과학교실) ;
  • 이경석 (경상대학교 의학전문대학원 성형외과학교실) ;
  • 김남균 (경상대학교 의학전문대학원 성형외과학교실) ;
  • 김준식 (경상대학교 의학전문대학원 성형외과학교실)
  • Lee, Yoon-Jung (Department of Plastic and Reconstructive Surgery, Institute of Health Sciences, College of Medicine and Hospital, Gyeongsang National University) ;
  • Lee, Kyung-Suk (Department of Plastic and Reconstructive Surgery, Institute of Health Sciences, College of Medicine and Hospital, Gyeongsang National University) ;
  • Kim, Nam-Gyun (Department of Plastic and Reconstructive Surgery, Institute of Health Sciences, College of Medicine and Hospital, Gyeongsang National University) ;
  • Kim, Jun-Sik (Department of Plastic and Reconstructive Surgery, Institute of Health Sciences, College of Medicine and Hospital, Gyeongsang National University)
  • 투고 : 2010.09.29
  • 심사 : 2011.01.06
  • 발행 : 2011.03.10

초록

Purpose: Mucinous eccrine carcinoma of the skin is rare skin adnexal malignant tumor, which most commonly occurs in the head and neck regions. This tumor, although rarely metastatic, has a high incidence of local recurrence. We report a case of mucinous eccrine carcinoma developed on the Lt. cheek which was treated by Mohs surgery. Methods: The patient was a 53-year-old man who showed a palpable skin-colored $1.5{\times}1.5cm$ sized mass on Lt. cheek. We treated it by wide excision, but it recurred several times on the same region. So we finally did the Mohs surgery and full thickness skin graft. Results: The histologic characteristics are large mucinous pools with fibrous septae and clusters of tumor cells. Special stains showed that the mucin was positive reactivity on Periodic acid Schiff. Also the immunocytochemical studies showed a positive reactivity to carcinoembryonic antigen, S-100 protein, cytokeratin-7. Therefore pathologist reported it as a mucinous eccrine carcinoma. Conclusion: Authors experienced a rare case of primary mucinous eccrine carcinoma on Lt. cheek which had recurred several times. Because of the high local recurrence rate, we did the Mohs surgery and got an good result. Therefore the early Mohs surgery would be a good choice to primary mucinous eccrine carcinoma.

키워드

참고문헌

  1. Lennox B, Pearse AG, Richards HG: Mucin-secreating tumours of the skin with special reference to the so-called mixed-salivary tumour of the skin and its relation to hidradenoma. J Pathol Bacteriol 64: 865, 1952 https://doi.org/10.1002/path.1700640418
  2. Kim JB, Choi JH, Kim JH, Park HJ, Lee JS, Joh OJ, Song KY: A case of primary cutaneous mucinous carcinoma with neuroendocrine differentiation. Ann Dermatol 22: 472, 2010 https://doi.org/10.5021/ad.2010.22.4.472
  3. Kim YJ, Kang HY, Lee ES, Kim YC: A case of primary cutaneous mucinous adenocarcinoma. Korean J Dermatol 44: 1098, 2006
  4. Karimipour DJ, Johnson TM, Kang S, Wang TS, Lowe L: Mucinous carcinoma of the skin. J Am Acad Dermatol 34: 323, 1996 https://doi.org/10.1016/S0190-9622(96)80151-4
  5. Mendoza S, Helwig EB: Mucinous (adenocytic) carcinoma of the skin. Arch Dermatol 103: 68, 1971 https://doi.org/10.1001/archderm.1971.04000130070011
  6. Scholz IM, Hartschuh W: Primary mucinous eccrine carcinoma of the skin-a rare clinical tumor with many differential diagnoses. J Dtsch Dermatol Ges 8: 446, 2010 https://doi.org/10.1111/j.1610-0387.2009.07291_supp.x
  7. Snow SN, Reizner GT. Dudley C, Mohs F: Eccrine mucinous carcinoma, Cutaneous oncology. 1st ed, Malden, Balckwell, 1998, p 758
  8. Kim MB, Oh CK, Jang HS, Kwon KS: A case of primary mucinous eccrin ecarcinoma of the skin treated by Mohs micrographic surgery. Korean J Dermatol 44: 1106, 2000
  9. Wildemore JK, Lee JB, Humphreys TR: Mohs surgery for malignant eccrine neoplasms. Dermatol Surg 30: 1574, 2004 https://doi.org/10.1111/j.1524-4725.2004.30569.x