Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지
DOI QR코드

DOI QR Code

Varicella-Zoster Virus Pneumonia in Immunocompetent Adults

정상 면역 성인에서 발생한 수두 폐렴 1예

  • Oh, Jee-Youn (Division of Pulmonary, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Choi, Jung-Woo (Department of Pathology, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Kim, Se-Joong (Division of Pulmonary, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Shin, Chol (Division of Pulmonary, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Kim, Je-Hyeong (Division of Pulmonary, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine)
  • 오지연 (고려대학교 의과대학 고려대학교 안산병원 호흡기내과학교실) ;
  • 최정우 (고려대학교 의과대학 고려대학교 안산병원 병리학교실) ;
  • 김세중 (고려대학교 의과대학 고려대학교 안산병원 호흡기내과학교실) ;
  • 신철 (고려대학교 의과대학 고려대학교 안산병원 호흡기내과학교실) ;
  • 김제형 (고려대학교 의과대학 고려대학교 안산병원 호흡기내과학교실)
  • Received : 2011.08.31
  • Accepted : 2011.10.12
  • Published : 2011.10.30
Download PDF
⟨ Previous Next ⟩

Abstract

Varicella, more commonly known as chickenpox, is caused by the varicella-zoster virus. It is a common benign childhood illness. In adults, Varicella is uncommon but is more severely associated with complications including pneumonia, hepatitis, disseminated intravascular coagulation, encephalitis and myocarditis. A serious and life-threatening complication is the development of varicella-zoster virus pneumonia (VZVP). Although VZVP is well described in immunocompromised hosts, it is rarely seen in immunocompetent adults. The VZVP in healthy adults is more prevalent in cigarette smokers and during pregnancy. However, reports of VZVP in healthy adults are scarce in Korea. The authors report here a case of VZVP in an immunocompetent adult and present a literature review.

Keywords

References

  1. Gregorakos L, Myrianthefs P, Markou N, Chroni D, Sakagianni E. Severity of illness and outcome in adult patients with primary varicella pneumonia. Respiration 2002;69:330-4. https://doi.org/10.1159/000063274
  2. Mohsen AH, McKendrick M. Varicella pneumonia in adults. Eur Respir J 2003;21:886-91. https://doi.org/10.1183/09031936.03.00103202
  3. Jones AM, Thomas N, Wilkins EG. Outcome of varicella pneumonitis in immunocompetent adults requiring treatment in a high dependency unit. J Infect 2001;43:135-9. https://doi.org/10.1053/jinf.2001.0874
  4. Haake DA, Zakowski PC, Haake DL, Bryson YJ. Early treatment with acyclovir for varicella pneumonia in otherwise healthy adults: retrospective controlled study and review. Rev Infect Dis 1990;12:788-98. https://doi.org/10.1093/clinids/12.5.788
  5. Shin YM, Moon SK, Kim CW, Shin DH, Choi JS, Kim KH. A case of varicella pneumonia in healthy adult. Korean J Dermatol 2007;45:394-6.
  6. Kim JS, Ryu CW, Lee SI, Sung DW, Park CK. High-resolution CT findings of varicella-zoster pneumonia. AJR Am J Roentgenol 1999;172:113-6. https://doi.org/10.2214/ajr.172.1.9888749
  7. Pugh RN, Omar RI, Hossain MM. Varicella infection and pneumonia among adults. Int J Infect Dis 1998;2:205-10. https://doi.org/10.1016/S1201-9712(98)90054-6
  8. Mohsen AH, Peck RJ, Mason Z, Mattock L, McKendrick MW. Lung function tests and risk factors for pneumonia in adults with chickenpox. Thorax 2001;56:796-9. https://doi.org/10.1136/thorax.56.10.796
  9. Wallace MR, Bowler WA, Oldfield EC 3rd. Treatment of varicella in the immunocompetent adult. J Med Virol 1993;Suppl 1:90-2.
  10. Nilsson A, Ortqvist A. Severe varicella pneumonia in adults in Stockholm County 1980-1989. Scand J Infect Dis 1996;28:121-3. https://doi.org/10.3109/00365549609049061
  11. Mer M, Richards GA. Corticosteroids in life-threatening varicella pneumonia. Chest 1998;114:426-31. https://doi.org/10.1378/chest.114.2.426
  12. Cowl CT, Prakash UB, Shawn Mitchell P, Migden MR. Varicella-zoster virus detection by polymerase chain reaction using bronchoalveolar lavage specimens. Am J Respir Crit Care Med 2000;162:753-4. https://doi.org/10.1164/ajrccm.162.2.9912039