DOI QR코드

DOI QR Code

A Case of Endobronchial Carcinoid Tumor Treated by Flexible Bronchoscopic Resection

기관지내시경 절제술로 치료한 기관지 카르시노이드 종양 1예

  • Na, Yong-Sub (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Yoon, Sung-Ho (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Lee, Seung-Il (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Kwon, Yong-Eun (Department of Internal Medicine, Chosun University College of Medicine)
  • 나용섭 (조선대학교 의과대학 내과학교실) ;
  • 윤성호 (조선대학교 의과대학 내과학교실) ;
  • 이승일 (조선대학교 의과대학 내과학교실) ;
  • 권용은 (조선대학교 의과대학 내과학교실)
  • Received : 2011.04.05
  • Accepted : 2011.05.07
  • Published : 2011.06.30

Abstract

Bronchial carcinoid tumor accounts for less than 5% of all primary lung tumors in adults. Although surgical resection is the treatment of choice, here we report a case of bronchial carcinoid tumor treated with flexible bronchoscopic resection. A 19-year-old-man presented with a history of wheezing with dyspnea for six months. A simple chest x-ray showed no abnormal findings, but a pulmonary function test showed a moderate obstructive lung disease pattern without a bronchodilator response. A computed tomogram of the thorax revealed an enhanced $15{\times}12$ mm nodule in the left main bronchus. Bronchoscopic examination showed a polypoid mass with a stalk in the left main bronchus, which almost completely occluded the left main bronchus. Histopathology of the resected specimen revealed a bronchial carcinoid tumor. We treated the carcinoid tumor with a flexible bronchoscopic resection. During the follow up period of 6 months, the previous tumor didn't relapse. Initial bronchoscopic resection should be considered when bronchial carcinoid tumor can be approached by bronchoscopy.

Keywords

References

  1. Tavis WD, Rush W, Flieder DB, Falk R, Fleming MV, Gal AA, et al. Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid. Am J Surg Pathol 1998;22:934-44. https://doi.org/10.1097/00000478-199808000-00003
  2. Mezzetti M, Raveglia F, Panigalli T, Giuliani L, Lo Giudice F, Meda S, et al. Assessment of outcomes in typical and atypical carcinoids according to latest WHO classification. Ann Thorac Surg 2003;76:1838-42. https://doi.org/10.1016/S0003-4975(03)01194-9
  3. Hage R, de la Riviere AB, Seldenrijk CA, van den Bosch JM. Update in pulmonary carcinoid tumors: a review article. Ann Surg Oncol 2003;10:697-704. https://doi.org/10.1245/ASO.2003.09.019
  4. Fuks L, Fruchter O, Amital A, Fox BD, Rahman NA, Kramer MR. Long-term follow-up of flexible bronchoscopic treatment for bronchial carcinoids with curative intent. Diagn Ther Endosc 2009;2009:782961.
  5. Soga J, Yakuwa Y. Bronchopulmonary carcinoids: an analysis of 1,875 reported cases with special reference to a comparison between typical carcinoids and atypical varieties. Ann Thorac Cardiovasc Surg 1999;5:211-9.
  6. Luckraz H, Amer K, Thomas L, Gibbs A, Butchart EG. Long-term outcome of bronchoscopically resected endobronchial typical carcinoid tumors. J Thorac Cardiovasc Surg 2006;132:113-5. https://doi.org/10.1016/j.jtcvs.2006.01.061
  7. Iglesias M, Belda J, Baldo X, Gimferrer JM, Catalan M, Rubio M, et al. Bronchial carcinoid tumor: a retrospective analysis of 62 surgically treated cases. Arch Bronconeumol 2004;40:218-21.
  8. van Boxem TJ, Venmans BJ, van Mourik JC, Postmus PE, Sutedja TG. Bronchoscopic treatment of intraluminal typical carcinoid: a pilot study. J Thorac Cardiovasc Surg 1998;116:402-6. https://doi.org/10.1016/S0022-5223(98)70005-4
  9. Bertoletti L, Elleuch R, Kaczmarek D, Jean-Francois R, Vergnon JM. Bronchoscopic cryotherapy treatment of isolated endoluminal typical carcinoid tumor. Chest 2006;130:1405-11. https://doi.org/10.1378/chest.130.5.1405
  10. Davila DG, Dunn WF, Tazelaar HD, Pairolero PC. Bronchial carcinoid tumors. Mayo Clin Proc 1993;68:795-803. https://doi.org/10.1016/S0025-6196(12)60641-7
  11. Thomas R, Christopher DJ, Balamugesh T, Shah A. Clinico-pathologic study of pulmonary carcinoid tumours--a retrospective analysis and review of literature. Respir Med 2008;102:1611-4. https://doi.org/10.1016/j.rmed.2008.05.003
  12. Rai SP, Patil AP, Vardhan V, Kumar R, Bhattacharya P, Pethe M. Intraluminal bronchial carcinoid resection by bronchoscopy. MJAFI 2008;64:86-8.
  13. Cavaliere S, Foccoli P, Toninelli C. Curative bronchoscopic laser therapy for surgically resectable tracheobronchial tumors: personal experience. J Bronchol Intervent Pulmonol 2002;9:90-95.
  14. Lee DS, Lee TW, Kim GY, Kim HJ, Song SH, Kim SC, et al. A case of bronchopulmonary atypical carcinoid tumor with liver metastasis. Tuberc Respir Dis 1996;43:623-9. https://doi.org/10.4046/trd.1996.43.4.623