DOI QR코드

DOI QR Code

Sarcoidosis Occured after Treatment of Tuberculous Lymphadenitis

결핵성 림프절염 치료 후 발생한 사르코이드증 1예

  • Lee, Hyo-Jeong (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Yoon, Sun-Young (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Han, Ji-Min (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • An, Ji-Hyun (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jeong-Ju (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Choi, Chang-Min (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Oh, Yeon-Mok (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shim, Tae-Sun (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sang-Do (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Woo-Sung (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Dong-Soon (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Song, Jin-Woo (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 이효정 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 윤선영 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 한지민 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 안지현 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 이정주 (울산대학교 의과대학 서울아산병원 병리학교실) ;
  • 최창민 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 오연목 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 심태선 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 이상도 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 김우성 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 김동순 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 송진우 (울산대학교 의과대학 서울아산병원 호흡기내과학교실)
  • Received : 2011.02.07
  • Accepted : 2011.04.10
  • Published : 2011.05.30

Abstract

Sarcoidosis is a multisystemic disorder characterized by the presence of non-caseating granulomas in the involved organ. Tuberculosis is an infectious disease caused by $Mycobacterium$ $tuberculosis$ and is characterized by granuloma with caseous necrosis. The clinical and histological similarity between sarcoidosis and tuberculosis has stimulated research searching for an association between mycobacterium and sarcoidosis. We report a case of a 38-year-old male with sarcoidosis that developed soon after treatment of tuberculous lymphadenitis. He was diagnosed as tuberculous lymphadenitis by microbiological confirmation. He showed clinical improvement after treatment for tuberculosis. One year later, his chest radiography showed bilateral hilar enlargement with diffuse bilateral nodules. A noncaseating granuloma was confirmed by endobronchial ultrasound guided transbronchial needle aspiration and he was diagnosed with sarcoidosis. To our knowledge, this is the first report describing sarcoidosis after treatment of tuberculosis in South Korea.

Keywords

References

  1. House JI, Ayele B, Porco TC, Zhou Z, Hong KC, Gebre T, et al. Assessment of herd protection against trachoma due to repeated mass antibiotic distributions: a cluster-randomised trial. Lancet 2009;373:1111-8. https://doi.org/10.1016/S0140-6736(09)60323-8
  2. Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis. N Engl J Med 2007;357:2153-65. https://doi.org/10.1056/NEJMra071714
  3. Semenzato G. ACCESS: a case control etiologic study of sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 2005;22:83-6.
  4. Drake WP, Newman LS. Mycobacterial antigens may be important in sarcoidosis pathogenesis. Curr Opin Pulm Med 2006;12:359-63. https://doi.org/10.1097/01.mcp.0000239554.01068.94
  5. Gal AA, Koss MN. The pathology of sarcoidosis. Curr Opin Pulm Med 2002;8:445-51. https://doi.org/10.1097/00063198-200209000-00018
  6. Scadding JG. Mycobacteria and sarcoidosis. Clinical studies support link. BMJ 1993;306:1269-70.
  7. Song Z, Marzilli L, Greenlee BM, Chen ES, Silver RF, Askin FB, et al. Mycobacterial catalase-peroxidase is a tissue antigen and target of the adaptive immune response in systemic sarcoidosis. J Exp Med 2005;201:755-67. https://doi.org/10.1084/jem.20040429
  8. Hatzakis K, Siafakas NM, Bouros D. Miliary sarcoidosis following miliary tuberculosis. Respiration 2000;67:219-22. https://doi.org/10.1159/000029492
  9. Mise K, Goic-Barisic I, Puizina-Ivic N, Barisic I, Tonkic M, Peric I. A rare case of pulmonary tuberculosis with simultaneous pulmonary and skin sarcoidosis: a case report. Cases J 2010;3:24. https://doi.org/10.1186/1757-1626-3-24
  10. Carlisle J, Evans W, Hajizadeh R, Nadaf M, Shepherd B, Ott RD, et al. Multiple Mycobacterium antigens induce interferon-gamma production from sarcoidosis peripheral blood mononuclear cells. Clin Exp Immunol 2007;150:460-8. https://doi.org/10.1111/j.1365-2249.2007.03510.x
  11. Chen ES, Wahlstrom J, Song Z, Willett MH, Wiken M, Yung RC, et al. T cell responses to mycobacterial catalase- peroxidase profile a pathogenic antigen in systemic sarcoidosis. J Immunol 2008;181:8784-96. https://doi.org/10.4049/jimmunol.181.12.8784
  12. Gupta D, Agarwal R, Aggarwal AN, Jindal SK. Molecular evidence for the role of mycobacteria in sarcoidosis: a meta-analysis. Eur Respir J 2007;30:508-16. https://doi.org/10.1183/09031936.00002607
  13. Hajizadeh R, Sato H, Carlisle J, Nadaf MT, Evans W, Shepherd BE, et al. Mycobacterium tuberculosis Antigen 85A induces Th-1 immune responses in systemic sarcoidosis. J Clin Immunol 2007;27:445-54. https://doi.org/10.1007/s10875-007-9080-4
  14. Poulter LW, Rossi GA, Bjermer L, Costabel U, Israel-Biet D, Klech H, et al. The value of bronchoalveolar lavage in the diagnosis and prognosis of sarcoidosis. Eur Respir J 1990;3:943-4.
  15. Judson MA. The diagnosis of sarcoidosis. Clin Chest Med 2008;29:415-27. https://doi.org/10.1016/j.ccm.2008.03.009