Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 21 Issue 4
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- Pages.353-363
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- 2011
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
Adverse Drug Reactions with Oseltamivir Treatment in the South Korea Outbreak of 2009 Pandemic Influenza A(H1N1)
2009년 국내 신종플루 유행시기의 Oseltamivir 부작용 평가
- Do, Youn-A (CHA Bundang Medical Center, CHA University) ;
- Lee, Suk-Hyang (College of Pharmacy, Ajou University)
- Received : 2011.11.07
- Accepted : 2011.12.05
- Published : 2011.12.31
Abstract
The World Health Organization (WHO) declared the outbreak of H1N1 pandemic in 2009. South Korea also had outbreaks of H1N1 virus and used oseltamivir in large volume with increased reports of adverse drug reaction(ADR). The present study was aimed to investigate the ADR frequency, the factors related to ADR, and characteristics of oseltamivir's ADR. Participants for the study were patients randomly drawn from those who were prescribed oseltamivir for treatment from CHA Bundang Medical Center during October 1 and October 30. The information examined as factors related to ADR were collected by a subsequent cross-sectional telephone survey. The factors are the following; a) age; b) gender; c) patient medical history; d) diagnosis of H1N1 virus; e) adherence; f) whether taking other medication with oseltamivir or not; and g) the number of combined medications. We also asked ADR after taking oseltamivir. Total subjects were 86 patients. The average age is