Hepatocellular Carcinoma with Bile Duct Tumor Thrombi

담도 종양 혈전을 동반한 간세포암종

  • Shin, Hye-Sun (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Hong, Ji-Young (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Han, Jung-Woo (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Doh, Fa-Mee (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Kim, Gi-Jeong (Department of Pathology, College of Medicine, Yonsei University) ;
  • Kim, Do-Young (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Ahn, Sang-Hoon (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Choi, Gi-Hong (Department of Surgery, College of Medicine, Yonsei University)
  • 신혜선 (연세대학교 의과대학 내과학교실) ;
  • 홍지영 (연세대학교 의과대학 내과학교실) ;
  • 한정우 (연세대학교 의과대학 내과학교실) ;
  • 도화미 (연세대학교 의과대학 내과학교실) ;
  • 김기정 (연세대학교 의과대학 병리학교실) ;
  • 김도영 (연세대학교 의과대학 내과학교실) ;
  • 안상훈 (연세대학교 의과대학 내과학교실) ;
  • 최기홍 (연세대학교 의과대학 외과학교실)
  • Published : 2011.12.30

Abstract

Obstruction of the bile duct owing to the direct extension of a tumor is occasionally found in patients with a hepatic neoplasm, but bile duct tumor thrombus caused by the intrabiliary transplantation of a free-floating tumor is a rare complication of hepatocellular carcinoma A 50-year-old woman was diagnosed with HCC with bile duct tumor thrombi. She received transarterial chemoembolization (TACE) because her liver function was not suitable for surgery at the time of diagnosis. After TACE, infected biloma occurred recurrently. Thus, resection of the HCC, including the bile duct tumor thrombi, was performed. Six months after the surgery, recurred HCC in the distal common bile duct as drop metastasis was noted. The patient was treated with tomotherapy and has been alive for three years as of this writing, without recurrence. The prognosis of HCC with bile duct tumor thrombi is considered dismal, but if appropriate procedures are selected and are actively carried out, long-term survival can occasionally be achieved.

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