Journal of computational fluids engineering (한국전산유체공학회지)

Korean Society of Computational Fluids Engineering (한국전산유체공학회)
권호 표지
DOI QR코드

DOI QR Code

EFFEECTS OF NON-NEWTONIAN FLUID MODEL ON HEMODYNAMICS IN CEREBRAL SACCULAR ANEURYSMS

낭상 뇌동맥류 혈류유동에서 비뉴우토니안 유체 모델의 영향

  • 박진석 (울산대학교 일반대학원 기계자동차공학과) ;
  • 이상욱 (울산대학교 기계공학부)
  • Received : 2011.03.03
  • Accepted : 2011.05.11
  • Published : 2011.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

The importance of shear thinning non-Newtonian blood rheology on the hemodynamic characteristics of idealized cerebral saccular aneurysms were investigated by carrying out CFD simulations assuming two different non-Newtonian rheology models (Carreau and Ballyk models). To explore effects of vessel curvature, a straight and a curved vessel geometry were considered. The wall shear stress(WSS), relative residence time(RRT) and velocity distribution were compared at the different phases of cardiac cycle. As expected, blood entered the aneurysm at the distal neck and created large vortex in both aneurysms, but with higher momentum on the curved vessel. Hemodynamic characteristics such as WSS, and RRT exhibited only minor effects by choice of different rheological models although Ballyk model produced relatively higher effects. We conclude that the assumption of Newtonian fluid is reasonable for studies aimed at quantifying the hemodynamic characteristics, in particular, WSS-based parameters, considering the current accuracy level of medical image of cerebral aneurysm.

Keywords

References

  1. 1998, Rinkel, G., Djibuti, M.., Algra, A.. and van Gijn, J. "Prevalence and risk of rupture of intracranial aneurysms: a systematic review," Stroke, Vol.29, pp.251-256. https://doi.org/10.1161/01.STR.29.1.251
  2. 2003, Wiebers, D., Whisnant, J., Huston, J., Meissner, I., Brown, R., Piepgras, D., Forbes, G.. and Thielen, K., et al., "Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment," Lancet, Vol.362, pp.103-110. https://doi.org/10.1016/S0140-6736(03)13860-3
  3. 2009, Ishibashi, T., Murayama, Y., Urashima, M., Saguchi, T., Ebara, M., Arakawa, H., Irie, K., Takao, H.. and Abe, T., "Unruptured intracranial aneurysms: incidence of rupture and risk factors," Stroke, Vol.40, pp.313-316. https://doi.org/10.1161/STROKEAHA.108.521674
  4. 2006, Valencia, A., Guzmán, A., Finol, E.. and Amon, C., "Blood flow dynamics in saccular aneurysm models of the basilar artery," J. Biomech. Eng., Vo.128, pp.516-526 https://doi.org/10.1115/1.2205377
  5. 2003, Steinman, D., Milner, J., Norley, C., Lownie, S. and Holdsworth, D., "Image-based computational simulation of flow dynamics in a giant intracranial aneurysm," AJNR Am. J. Neuroradiol., Vol.24, pp.559-566.
  6. 2010, Sforza, D., Putman, C., Scrivano, E., Lylyk, P. andCebral, J., "Blood-flow characteristics in a terminal basilar tip aneurysm prior to its fatal rupture," AJNR Am. J. Neuroradiol., Vol.31, pp.1127-1131. https://doi.org/10.3174/ajnr.A2021
  7. 2007, Lee, S. and Steinman, D., "On the relative importance of rheology for image-based CFD models of the carotid bifurcation," J. Biomech. Eng., Vol.129 pp.273-278. https://doi.org/10.1115/1.2540836
  8. 2006, O'Callaghan, S., Walsh, M.. and McGloughlin, T., "Numerical modeling of Newtonian and non-Newtonian representation of blood in a distal end-to-side vascular bypass graft anastomosis," Med. Eng. Phys., Vol.28, pp.70-74 https://doi.org/10.1016/j.medengphy.2005.04.001
  9. 2004, Johnston, B., Johnston, P., Corney, S. and Kilpatrick, D., "Non-Newtonian blood flow in human right coronary arteries: steady state simulations," J. Biomech., Vol.37, pp.709-720. https://doi.org/10.1016/j.jbiomech.2003.09.016
  10. 2004, Stuhne, G.R. and Steinman, D.A., "Finite-element modeling of the hemodynamics of stented aneurysms," J. Biomech. Eng., Vol.126, pp.382-387. https://doi.org/10.1115/1.1762900
  11. 2005, Ford, M., Stuhne, G., Nikolov, H., Habets, D. and Lownie, S., Holdsworth, D., Steinman, D.A., "Virtual angiography for visualization and validation of computational models of aneurysm hemodynamics," IEEE Trans. Med.Imaging., Vol.24, pp.1586-1592. https://doi.org/10.1109/TMI.2005.859204
  12. 2005, Seo, T., Schachter, L. and Barakat, A., "Computational study of fluid mechanical disturbance induced by endovascular stents," Ann. Biomed. Eng., Vol.33, pp.444-456. https://doi.org/10.1007/s10439-005-2499-y
  13. 1994, Ballyk, P., Steinman, D.A. and Ethier, C., "Simulation of non-newtonian blood flow in an end-to-side anastomosis," Biorheology, Vol.31, pp.565-586. https://doi.org/10.3233/BIR-1994-31505
  14. 1982, Biro, G., "Comparison of acute cardiovascular effects and oxygen-supply following haemodilution with dextran, stroma-free haemoglobin solution and fluorocarbon suspension," Cardiovasc. Res., Vol.16, pp.194-204. https://doi.org/10.1093/cvr/16.4.194
  15. 2004, Himburg, H., Grzybowski, D., Hazel, A., LaMack. and J., Li, X., Friedman, M., "Spatial comparison between wall shear stress measures and porcine arterial endothelial permeability," Am. J. Physiol. Heart. Circ. Phys., Vol.286, pp.H1916-1922. https://doi.org/10.1152/ajpheart.00897.2003
  16. 2008, Rayz, V., Boussel, Lawton, M., Acevedo-Bolton, G., Ge, L., Young, W., Higashida, R. and Saloner, D., "Numerical modeling of the flow in intracranial aneurysms: prediction of regions prone to thrombus formation," Ann. Biomed. Eng., Vol.36, pp.1793-1804. https://doi.org/10.1007/s10439-008-9561-5