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Calcifying epithelial odontogenic tumor (CEOT) in palate: report of a case

구개에 발생한 석회화 상피성 치성 종양: 증례보고

  • Kim, Joong-Min (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University) ;
  • Jang, Hyon-Seok (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University) ;
  • Rim, Jae-Suk (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University) ;
  • Jun, Sang-Ho (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University) ;
  • Park, Jung-Kyun (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University) ;
  • Ju, Hyun-Joong (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University) ;
  • Lee, Eui-Seok (Department of Oral and Maxillofacial Surgery, College of Medicine, Korea University)
  • 김중민 (고려대학교 의과대학 구강악안면외과학교실) ;
  • 장현석 (고려대학교 의과대학 구강악안면외과학교실) ;
  • 임재석 (고려대학교 의과대학 구강악안면외과학교실) ;
  • 전상호 (고려대학교 의과대학 구강악안면외과학교실) ;
  • 박정균 (고려대학교 의과대학 구강악안면외과학교실) ;
  • 주현중 (고려대학교 의과대학 구강악안면외과학교실) ;
  • 이의석 (고려대학교 의과대학 구강악안면외과학교실)
  • Received : 2010.11.07
  • Accepted : 2011.02.09
  • Published : 2011.02.28

Abstract

A calcifying epithelial odontogenic tumor (CEOT) was first described as a separate entity in 1955 by Pindborg, and has since been referred to as Pindborg tumor. CEOT is characterized by the presence of squamous-cell proliferation, calcification and amyloid deposits, and accounts for only 1% of all odontogenic tumors. CEOT is a benign, though occasional locally invasive, slow-growing neoplasm. It is located either intraosseously or extraosseously, and is usually associated with an unerupted permanent tooth. A 24 year-old female visited our clinic, presenting with a palatal swelling and intra-oral ulcer. After an incisional biopsy, the lesion was confirmed to be odontogenic tumor. A tumor resection and reconstruction surgery with tongue flap were performed.

Keywords

References

  1. Pindborg JJ. Calcifying epithelial odontogenic tumors. APMIS 1955;111 Suppl:71.
  2. Anavi Y, Kaplan I, Citir M, Calderon S. Clear-cell variant of calcifying epithelial odontogenic tumor: clinical and radiographic characteristics. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:332-9. https://doi.org/10.1067/moe.2003.8
  3. Korean Academy of Oral and Maxillofacial Radiology, ed. Oral and Maxillofacial Radiology. 2nd ed. Seoul: Yiwoo; 1996.
  4. Sapp JP, Eversole LR, Wysocki GP. Contemporary oral and maxillofacial pathology. St. Louis, Mo.: Mosby; 1998.
  5. Lim CY, Hong SP, Lee JI. Color atlas of oral pathology. 2nd ed. Seoul: Korea Medical Book; 1999.
  6. Maiorano E, Renne G, Tradati N, Viale G. Cytogical features of calcifying epithelial odontogenic tumor (Pindborg tumor) with abundant cementum-like material. Virchows Arch 2003;442:107-10.
  7. Bouckaert MM, Raubenheimer EJ, Jacobs FJ. Calcifying epithelial odontogenic tumor with intracranial extension: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;90:656-62. https://doi.org/10.1067/moe.2000.106577
  8. Belmonte-Caro R, Torres-Lagares D, Mayorga-Jimenez F, Garcia-Perla Garcla A, Infante-Cossio P, Gutierrez-Perez JL. Calcifying epithelial odontogenic tumor (Pindborg tumor). Med Oral 2002;7:309-15.
  9. Veness MJ, Morgan G, Collins AP, Walker DM. Calcifying epithelial odontogenic (Pindborg) tumor with malignant transformation and metastatic spread. Head Neck 2001;23:692-6. https://doi.org/10.1002/hed.1097
  10. Philipsen HP, Reichart PA. Calcifying epithelial odontogenic tumour: biological profile based on 181 cases from the literature. Oral Oncol 2000;36:17-26. https://doi.org/10.1016/S1368-8375(99)00061-5
  11. Martin-Duverneuil N, Roisin-Chausson MH, Behin A, Favre- Dauvergne E, Chiras J. Combined benign odontogenic tumors: CT and MR findings and histomorphologic evaluation. AJNR Am J Neuroradiol 2001;22:867-72.
  12. Cheng YS, Wright JM, Walstad WR, Finn MD. Calcifying epithelial odontogenic tumor showing microscopic features of potential malignant behavior. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:287-95. https://doi.org/10.1067/moe.2002.121991
  13. Cross JJ, Pilkington RJ, Antoun NM, Adlam DM. Value of computed tomography and magnetic resonance imaging in the treatment of a calcifying epithelial odontogenic (Pindborg) tumour. Br J Oral Maxillofac Surg 2000;38:154-7. https://doi.org/10.1054/bjom.1999.0148
  14. Crivelini MM, de Araujo VC, de Sousa SO, de Araujo NS. Cytokeratins in epithelia of odontogenic neoplasms. Oral Dis 2003;9:1-6. https://doi.org/10.1034/j.1601-0825.2003.00861.x
  15. Mesquita RA, Lotufo MA, Sugaya NN, de Araujo NS, de Araujo VC. Peripheral clear cell variant of calcifying epithelial odontogenic tumor: report of a case and immunohistochemical investigation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:198-204. https://doi.org/10.1067/moe.2003.63
  16. Iezzi G, Rubini C, Fioroni M, Piattelli A. Clear cell odontogenic carcinoma. Oral Oncol 2002;38:209-13. https://doi.org/10.1016/S1368-8375(01)00038-0
  17. Solomon A, Murphy CL, Weaver K, Weiss DT, Hrncic R, Eulitz M, et al. Calcifying epithelial odontogenic (Pindborg) tumor-associated amyloid consists of a novel human protein. J Lab Clin Med 2003;142:348-55. https://doi.org/10.1016/S0022-2143(03)00149-5