Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제37권1호
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  • Pages.9-14
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  • 2011
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  • 2234-7550(pISSN)
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  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
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Recombinant human erythropoietin을 이용한 무수혈 구강암절제 및 재건

Oral cancer resection and reconstruction without blood transfusion by using recombinant human erythropoietin

  • 김철환 (단국대학교 치과대학 구강악안면외과학교실) ;
  • 이충현 (단국대학교 치과대학 구강악안면외과학교실)
  • Kim, Chul-Hwan (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University) ;
  • Lee, Chung-Hyun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University)
  • 투고 : 2010.09.27
  • 심사 : 2011.01.20
  • 발행 : 2011.02.28
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초록

Recently, the population of patients who refuse transfusion has increased for both religious and non-religious reasons, even in life threatening emergency situations. Their refusal has highlighted the need to develop nonblood transfusion surgery techniques to decrease the risk from blood transfusions. A 57-year woman with an ulcerative lesion on the gingiva of the right upper molar area visited the department of oral and maxillofacial surgery in Dankook University Dental Hospital. After a preliminary evaluation, the patient was diagnosed with squamous cell carcinoma. As she refused blood transfusion during surgery for religious reasons, surgery was planned using recombinant human erythropoietin (rHuEPO) without a blood transfusion. The patient underwent a partial maxillectomy, supraomohyoid neck dissection, free radial forearm flap and split thickness skin graft under general anesthesia. rHuEPO and iron were used before and after surgery. The hemoglobin/hematocrit (Hb/Hct) level, iron (Fe) and total iron-binding capacity (TIBC) were assessed. The patient recovered completely without any blood transfusions. rHuEPO is a viable alternative for patients with religious objections to receiving blood transfusions.

키워드

참고문헌

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피인용 문헌

  1. Anatomical Study of the Mandibular Angle and Body in Wide Mandibular Angle Cases vol.38, pp.5, 2011, https://doi.org/10.1007/s00266-014-0370-y