Mood & Emotion (우울조울병)

Korean Society for Affective Disorders (대한우울조울병학회)
권호 표지

The Comorbidity of Anxiety Disorder in Depressed Patients : A CRESCEND(Clinical Research Center for Depression in Korea) Cohort Study

우울증 환자에서 불안장애의 동반이환 : 우울증 임상연구센터 코호트연구

  • Sakong, Jeong-Kyu (Department of Psychiatry, College of Medicine, Dongguk University) ;
  • Lee, Do-Yun (Department of Psychiatry, College of Medicine, Dongguk University) ;
  • Suh, Ho-Suk (Department of Psychiatry, School of Medicine, CHA University) ;
  • Sung, Hyung-Mo (Department of Psychiatry, School of Medicine, CHA University) ;
  • Kim, Jung-Bum (Department of Psychiatry, School of Medicine, Keimyung University) ;
  • Jung, Young-Eun (Department of Psychiatry, College of Medicine, Catholic University) ;
  • Lee, Min-Soo (Department of Psychiatry, College of Medicine, Korea University) ;
  • Kim, Jae-Min (Department of Psychiatry, College of Medicine, Chonnam National University) ;
  • Jo, Sunjin (Department of Preventive Medicine, College of Medicine, Catholic University)
  • 사공정규 (동국대학교 의과대학 정신과학교실) ;
  • 이도윤 (동국대학교 의과대학 정신과학교실) ;
  • 서호석 (CHA 의과대학 정신과학교실) ;
  • 성형모 (CHA 의과대학 정신과학교실) ;
  • 김정범 (계명대학교 의과대학 정신과학교실) ;
  • 정영은 (가톨릭대학교 의과대학 정신과학교실) ;
  • 이민수 (고려대학교 의과대학 정신과학교실) ;
  • 김재민 (전남대학교 의과대학 정신과학교실) ;
  • 조선진 (가톨릭대학교 의과대학 예방의학교실)
  • Received : 2010.10.29
  • Accepted : 2011.02.11
  • Published : 2011.02.28
⟨ Previous Next ⟩

Abstract

Purpose : Anxiety disorder and depressive disorder are often comorbid with each other, and the comorbidity is associated with poorer psychiatric outcome, resistance to treatment, increased risk for suicide, greater chance for recurrence. We aimed to investigate the comorbidity of anxiety disorder in Korea. Method : Subjects were total of 867 depressed patients recruited CRESCEND-K multicenter trial. We used SCID (Structured Clinical Interview for DSM - IV) to find comorbidity of anxiety disorders in depressed patient. Results : Of 867 patients, total 8.2% had anxiety disorder. Proportion of anxiety disorder Not Otherwise Specified was 3.5%, panic disorder was 1.7%, generalized anxiety disorder was 1.1%, post traumatic stress disorder was 0.9%, obsessive compulsive disorder was 0.6%, social phobia was 0.4%. Conclusion : In this study, anxiety disorder in depression were measured at a low comorbidity rate in compare to previous studies. Selection bias, use of antidepressants at registration, severity of depression symptoms, and point of SICD administration seems to have affected these results. It is probable that comorbidity evaluation would be more precise if shorter, structured interviews such as M. I.N.I.-Plus were used during first clinical interview for depression diagnosis.

Keywords

Acknowledgement

본 연구는 보건복지부 보건의료기술진흥사업의 지원에 의하여 이루어진 것임(과제번호 : A050047).