DOI QR코드

DOI QR Code

Bio-inspired leaf stent for direct treatment of cerebral aneurysms: design and finite element analysis

  • Zhou, Xiang (Department of Engineering Science, University of Oxford) ;
  • You, Zhong (Department of Engineering Science, University of Oxford) ;
  • Byrne, James M.D. (Department of Neuroradiology, Nuffield Department of Surgery, University of Oxford)
  • 투고 : 2010.08.05
  • 심사 : 2010.08.28
  • 발행 : 2011.07.25

초록

Cerebral aneurysm is common lesion among adult population. Current methods for treating the disease have several limitations. Inspired by fern leaves, we have developed a new stent, called leaf stent, which can provide a tailored coverage at the neck of an aneurysm and thus prevent the blood from entering the aneurysm. It alone can be used to treat the cerebral aneurysm and therefore overcomes problems existing in current treating methods. The paper focuses on the numerical simulation of the leaf stents. The mechanical behaviour of the stent in various designs has been investigated using the finite element method. It has been found that certain designs provide adequate radial force and have excellent longitudinal flexibility. The performance of certain leaf stents is comparable and even superior to those of the commercially available cerebral stents such as the Neuroform stent and the Enterprise stent, commonly used for stent assisted coiling, while at the same time, providing sufficient coverage to isolate the aneurysm without using coils.

키워드

참고문헌

  1. Fiorella, D., Albuquerque, F.C., Deshmukh, V.R., Woo, H.H., Rasmussen, P.A., Masaryk, T.J. and McDougall, C.G. (2006), "Endovascular Reconstruction with the Neuroform Stent as Monotherapy for the Treatment of Uncoilable Intradural Pseudoaneurysms", Neurosurgery, 59(2), 291-300. https://doi.org/10.1227/01.NEU.0000223650.11954.6C
  2. Brisman, J.L., Song, J.K. and Newell, D.W. (2006), "Cerebral Aneurysms", N. Engl. J. Med., 355(9), 928-939. https://doi.org/10.1056/NEJMra052760
  3. Kim, M., Taulbee, D.B., Tremmel, M. and Meng, H. (2008), "Comparison of two stents in modifying cerebral aneurysm hemodynamics", Ann. Biomed. Eng., 36(5), 726-741. https://doi.org/10.1007/s10439-008-9449-4
  4. Mitha, A.P. and Ogilvy, C.S. (2005), "ISAT: coiling or clipping for ruptured intracranial aneurysms?", Lancet Neurol., 4(12), 791-792. https://doi.org/10.1016/S1474-4422(05)70231-3
  5. Rebelo, N., Fu, R. and Lawrenchuk, M. (2009), "Study of a nitinol stent deployed into anatomicallyaccurate artery geometry and subjected to realistic service loading", J. Mater. Eng. Perform., 18(5-6), 655-663. https://doi.org/10.1007/s11665-009-9375-0
  6. Rebelo, N., Gong, X., Hall, A., Pelton, A.R. and Duerig, T.W. (2004), "Finite element analysis on the cyclic properties of superelastic nitinol", ABAQUS Users' Conference, 601-613.
  7. Wijdicks, E.F.M., Kallmes, D.F., Manno, E.M., Fulgham, J.R. and Piepgras, D.G. (2005), "Subarachnoid hemorrhage: neurointensive care and aneurysm repair", Mayo. Clin. Proc., 80(4), 550-559. https://doi.org/10.4065/80.4.550
  8. Zhou, X., You, Z. and Byrne, J. (2009), Stent, British Patent Application 0900565.3.

피인용 문헌

  1. Guided Ultrasonic Wave Imaging for Immersed Plates Based on Wavelet Transform and Probabilistic Analysis vol.25, pp.2, 2014, https://doi.org/10.1080/09349847.2013.837212
  2. Accelerated in vitro durability testing of nonvascular Nitinol stents based on the electrical potential sensing method vol.112, pp.4, 2013, https://doi.org/10.1007/s00339-012-7447-8
  3. An l p -norm approach to robust probabilistic inspection of plate-like structure defects with guided waves vol.26, pp.10, 2017, https://doi.org/10.1088/1361-665X/aa797e
  4. MECHANICAL CHARACTERIZATION OF BRAIDED SELF-EXPANDING STENTS: IMPACT OF DESIGN PARAMETERS vol.19, pp.6, 2011, https://doi.org/10.1142/s0219519419500386