Bulletin of the Korean Chemical Society

  • 제32권4호
  • /
  • Pages.1277-1281
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  • 2011
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Preparation and Characterization of Core/Shell-type Ag/Chitosan Nanoparticles with Antibacterial Activity

  • Lin, Yue (State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University) ;
  • Jing, Wang (State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University) ;
  • Kang, Pan (State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University) ;
  • Xiaoming, Zhang (State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University) ;
  • Zhouping, Wang (State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University) ;
  • Wenshui, Xia (State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University)
  • 투고 : 2010.12.14
  • 심사 : 2011.02.15
  • 발행 : 2011.04.20
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초록

Making use of chitosan (CS) and ethylenediaminetetraacetic acid (EDTA) as a reaction system, CS-EDTA nanoparticles were synthesized through a facile counterion complex coacervation method. $Ag^+$ could enter porous CS nanoparticles synthesized with this method, allowing Ag nanoparticles within chitosan nanoparticles were synthesized by reducing silver nitrate with chitosan. Because of the noncovalent interaction between CS and EDTA, the EDTA could be easily removed via dialysis against water, and pure core/shell-type Ag/CS nanoparticles could be obtained. The nanoparticles showed higher antibacterial activity toward E. coli than the active precursor Ag nanoparticles and CS.

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