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상악골에 발생한 각화법랑모세포종: 증례보고

Keratoameloblastoma of the maxilla: a case report

  • 원지훈 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 나혜영 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 김현실 (연세대학교 치과대학 구강종양연구소) ;
  • 김진 (연세대학교 치과대학 구강종양연구소) ;
  • 남웅 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 차인호 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 김형준 (연세대학교 치과대학 구강악안면외과학교실)
  • Won, Ji-Hoon (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Na, Hye-Young (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Hyun-Sil (Department of Oral Cancer Research Institute, College of Dentistry, Yonsei University) ;
  • Kim, Jin (Department of Oral Cancer Research Institute, College of Dentistry, Yonsei University) ;
  • Nam, Woong (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Cha, In-Ho (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Hyung-Jun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University)
  • 투고 : 2011.07.05
  • 심사 : 2011.10.12
  • 발행 : 2011.12.31

초록

A keratoameloblastoma is a histologically variant of the ameloblastoma group, which varies in size and contains keratin material in the fibrous connective tissue among cystic lesions. A keratoameloblastoma is a rare disease with only 13 cases reported in the literature since Pindborg's first report in 1970. A 41-year-old man visited, complaining of pus discharged from the right maxilla. He had been diagnosed with an odontogenic keratocyst and was treated with cyst enucleation in the past. The clinical and radiology examination found evidence of recurrence and finally diagnosed him with keratoameloblastoma after enucleation and biopsy. This report discusses the clinical, radiological and histological characteristics of keratoameloblastoma and its treatment. In addition, we report another case of keratoameloblastoma that had transformed from an odontogenic keratocyst.

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참고문헌

  1. Whitt JC, Dunlap CL, Sheets JL, Thompson ML. Keratoameloblastoma: a tumor sui generis or a chimera? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;104:368-76. https://doi.org/10.1016/j.tripleo.2006.07.025
  2. Pindborg JJ. Pathology of the dental hard tissues. 2nd ed. Philadelphia: Saunders; 1970.
  3. Altini M, Lurie R, Shear M. A case report of keratoameloblastoma. Int J Oral Surg 1976;5:245-9. https://doi.org/10.1016/S0300-9785(76)80020-8
  4. Norval EJ, Thompson IO, van Wyk CW. An unusual variant of keratoameloblastoma. J Oral Pathol Med 1994;23:465-7. https://doi.org/10.1111/j.1600-0714.1994.tb00446.x
  5. Altini M, Slabbert HD, Johnston T. Papilliferous keratoameloblastoma. J Oral Pathol Med 1991;20:46-8. https://doi.org/10.1111/j.1600-0714.1991.tb00887.x
  6. Siar CH, Ng KH. 'Combined ameloblastoma and odontogenic keratocyst' or 'keratinising ameloblastoma'. Br J Oral Maxillofac Surg 1993;31:183-6. https://doi.org/10.1016/0266-4356(93)90122-D
  7. Said-al-Naief NA, Lumerman H, Ramer M, Kopp W, Kringstein GJ, Persenchino F, et al. Keratoameloblastoma of the maxilla. A case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;84:535-9. https://doi.org/10.1016/S1079-2104(97)90270-5
  8. Takeda Y, Satoh M, Nakamura S, Ohya T. Keratoameloblastoma with unique histological architecture: an undescribed variation of ameloblastoma. Virchows Arch 2001;439:593-6. https://doi.org/10.1007/s004280100489
  9. Collini P, Zucchini N, Vessecchia G, Guzzo M. Papilliferous keratoameloblastoma of mandible: a papillary ameloblastic carcinoma: report of a case with a 6-year follow-up and review of the literature. Int J Surg Pathol 2002;10:149-55. https://doi.org/10.1177/106689690201000210
  10. Vered M, Buchner A, Dayan D, Shteif M, Laurian A. Solid variant of odontogenic keratocyst. J Oral Pathol Med 2004;33:125-8. https://doi.org/10.1111/j.1600-0714.2004.00014.x
  11. Ide F, Mishima K, Saito I. Solid-cystic tumor variant of odontogenic keratocyst: an aggressive but benign lesion simulating keratoameloblastoma. Virchows Arch 2003;442:501-3.
  12. Odell EW, Morgan PR. Biopsy pathology of the oral tissues. London: Chapman & Hall Medical; 1998.
  13. Partridge M, Towers JF, Towers JF. The primordial cyst (odontogenic keratocyst): its tumour-like characteristics and behaviour. Br J Oral Maxillofac Surg 1987;25:271-9. https://doi.org/10.1016/0266-4356(87)90065-9
  14. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behaviour. Oral Oncol 2002;38:219-26. https://doi.org/10.1016/S1368-8375(01)00065-3
  15. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies. Oral Oncol 2002;38:323-31. https://doi.org/10.1016/S1368-8375(01)00066-5