한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제28권6호
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  • Pages.586-590
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  • 2011
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

세 마리의 소형견에서 발생한 다양한 해부학적, 혈역학적, 병태생리학적 타입의 심방중격결손 비교 고찰 사례

Comparison of Different Anatomic, Hemodynamic, and Pathophysiological Types of Atrial Septal Defect in Three Small Dogs

  • 김정현 (건국대학교 수의과대학 내과학교실) ;
  • 문소정 (건국대학교 수의과대학 내과학교실) ;
  • 강민희 (건국대학교 수의과대학 내과학교실) ;
  • 김승곤 (건국대학교 수의과대학 내과학교실) ;
  • 박희명 (건국대학교 수의과대학 내과학교실)
  • Kim, Jung-Hyun (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Moon, So-Jeung (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Kang, Min-Hee (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Kim, Seung-Gon (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Park, Hee-Myung (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • 심사 : 2011.11.30
  • 발행 : 2011.12.31
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초록

5 kg 미만의 소형견 3마리가 호흡곤란과 심잡음을 주증상으로 내원하였다. 한 마리 환자에서는 일차 심방중격결손과 함께 유미흉이 진단되었다. 나머지 두 마리 환자들에서는 이차 심방중격결손이 확인되었으며, 이 중 한 마리의 환자에서는 폐동맥 협착증이 병발되었다. 내과적 치료를 시도하였으나, 이차 심방중격 결손을 가진 두 마리의 환자들은 폐사하였으며 일차 심방중격 결손이 있는 환자는 약물치료로 성공적으로 유지되었다. 폐사한 두 마리의 환자에 서는 부검을 통하여 결손부를 확인하였다. 본 증례의 경우, 세 마리의 소형견에서 발생한 다양한 해부학적, 혈역학적, 병태생리학적 타입의 심방중격 결손의 임상증상, 진단학적 특징을 대형견에서의 특징과 비교 분석한 첫 증례보고이다.

Three small breed dogs weighing less 5 kg were admitted with dyspnea and cardiac murmurs. One dog had primum type ASD and chylothorax was concurrently noted. Two dogs had secundum type ASD with and without concomitant pulmonic stenosis. Although medical treatment was attempted, two dogs with secundum type ASD died and a dog with primum type ASD was successfully managed with medication. Defects were confirmed by the postmortem examination in two cases. We first describe the comparison of clinical and diagnostic features in different anatomic, hemodynamic, and pathophysiological types of ASD in small breed dogs and they show some differences with ASD in large breed dogs.

키워드

참고문헌

  1. Amberger CN, Boujon CE, Amberger C, Boujon C. Atrioventricular Canal Defect (incomplete form of endocardial cushion defect) and Ostium Secundum Type Interatrial Septal defect in a dog. J Vet Cardiol 2002; 4: 37-41. https://doi.org/10.1016/S1760-2734(06)70037-6
  2. Boujon C, Amberger C, Lombard C. Right ventricular aneurysm and atrial septal defect in a cat. J Vet Cardiol 2004; 6: 44-48. https://doi.org/10.1016/S1760-2734(06)70057-1
  3. Chetboul V, Charles V, Nicolle A, Sampedrano CC, Gouni V, Pouchelon JL, Tissier R. Retrospective study of 156 atrial septal defects in dogs and cats (2001-2005). J Vet Med A Physiol Pathol Clin Med 2006; 53: 179-184. https://doi.org/10.1111/j.1439-0442.2006.00813.x
  4. Chetboul V, Trolle JM, Nicolle A, Carlos Sampedrano C, Gouni V, Laforge H, Benalloul T, Tissier R, Pouchelon JL. Congenital heart diseases in the boxer dog: A retrospective study of 105 cases (1998-2005). J Vet Med A Physiol Pathol Clin Med 2006; 53: 346-351. https://doi.org/10.1111/j.1439-0442.2006.00865.x
  5. Diana A, Guglielmini C, Acocella F, Valerio F, Cipone M. Chylothorax associated with tricuspid dysplasia and atrial septal defect in a bullmastiff. J Am Anim Hosp Assoc 2009; 45: 78-83. https://doi.org/10.5326/0450078
  6. Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 2003; 424: 443-447. https://doi.org/10.1038/nature01827
  7. Gordon SG, Miller MW, Roland RM, Saunders AB, Achen SE, Drourr LT, Nelson DA. Transcatheter atrial septal defect closure with the Amplatzer atrial septal occluder in 13 dogs: short- and mid-term outcome. J Vet Intern Med 2009; 23: 995-1002. https://doi.org/10.1111/j.1939-1676.2009.0365.x
  8. Guglielmini C, Diana A, Pietra M, Cipone M. Atrial septal defect in five dogs. J Small Anim Pract 2002; 43: 317-322. https://doi.org/10.1111/j.1748-5827.2002.tb00081.x
  9. Jeraj K, Ogburn PN, Johnston GR, Edwards W, Yano B, Brunson D, Wallace L, McGrath C. Atrial septal defect (sinus venosus type) in a dog. J Am Vet Med Assoc. 1980; 177: 342-346.
  10. Monnet E, Orton EC, Gaynor J, Boon J, Peterson D, Guadagnoli M. Diagnosis and surgical repair of partial atrioventricular septal defects in two dogs. J Am Vet Med Assoc 1997; 211: 569-572.
  11. Park C, Choi CB, Kim IH, Park HM. A case of Atrial Septal Defect in a Miniature Schnauzer Dog. Korean J Vet Res 2003; 43: 307-310.
  12. Santamarina G, Espino L, Vila M, Suarez ML. Partial atrioventricular canal defect in a dog. J Small Anim Pract 2002; 43: 17-21. https://doi.org/10.1111/j.1748-5827.2002.tb00004.x
  13. Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJ, Lai D, McDonald LP, Niederreither K, Dolle P, Bruneau BG, Zorn AM, Harvey RP. Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol 2003; 262: 206-224. https://doi.org/10.1016/S0012-1606(03)00385-3
  14. Tanaka R, Shimizu M, Hirao H, Kobayashi M, Nagashima Y, Machida N, Yamane Y. Surgical management of a doublechambered right ventricle and chylothorax in a Labrador retriever. J Small Anim Pract 2006; 47: 405-408. https://doi.org/10.1111/j.1748-5827.2006.00079.x