A Case of Cold Medicine-Induced Hepatitis Treated with Herbal Medicine

  • Son, Chang-Gue (Liver and Immunology Research Center, Oriental Medical College in Daejeon University)
  • Received : 2011.08.31
  • Accepted : 2011.10.25
  • Published : 2011.11.30

Abstract

Objectives: To inform the clinical features of drug-induced liver injury (DILI), and study traditional Korean medicine (TKM)-based strategies or therapeutics. Methods: A female patient with hepatitis after long term use of medication for cold symptoms was treated with Oriental therapies, after which the clinical outcome was evaluated by serum biochemical parameters and ultrasonography. Results: Clinical and biochemical levels were fluctuating during administration of cold medicine, but the patient completely recovered her health with herbal medicines. Conclusion: This case report would provide information about a typical DILI by western medicine followed by treatment with traditional Korean medicine.

Keywords

References

  1. Harvey RA, Champe PC, Howland RE, Mycek MJ. Lippincott's illustrated reviews: pharmacology. 3rd ed. Baltimore: Lippincot Williams & Wilkins. 2006: pp13-8.
  2. Ostapowicz G, Fontana RJ, Schiodt FV, Larson A, Davern TJ, Han SH, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med. 2002; 137:947-54. https://doi.org/10.7326/0003-4819-137-12-200212170-00007
  3. Navarro VJ, Senior JR. Drug-related hepatotoxicity. N Engl J Med. 2006; 354:731-9. https://doi.org/10.1056/NEJMra052270
  4. Ye XF, He J. The bright future of Chinese herbal medicine: only after a twisty road. Contemp Clin Trials. 2010; 31(6):508-9. https://doi.org/10.1016/j.cct.2010.07.007
  5. Bent S, Ko R. Commonly used herbal medicines in the United States: a review. Am J Med. 2004; 116(7):478-85. https://doi.org/10.1016/j.amjmed.2003.10.036
  6. Bent S. Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical Center. J Gen Intern Med. 2008; 23(6): 854-9. https://doi.org/10.1007/s11606-008-0632-y
  7. Park HM, Jang IS, Lee SD. Hepatotoxic Events Associated with Herbal Medicinal Products, Folk Remedies and Food Supplements in Korea. J Korean Oriental Med. 2005; 26(2):152-65.
  8. Kim DM, Kim HK, Cho SY, Kim YS, Nam SS. Retrospective Observation of Liver Function Parameters for 101 Patients Using Herbal Drugs for One Month. J Korean Oriental Med. 2010; 31(2):149-57.
  9. Yun YJ, Shin BC, Lee MS, Cho SI, Park JH, Lee HJ. Systematic Review of the Cause of Drug- Induced Liver Injuries in Korean Literature. J Korean Oriental Med. 2009; 30(2):30-45.
  10. Seo JC, Jeon WJ, Park SS, Kim SH, Lee KM, Chae HB, et al. Clinical experience of 48 acute The Journal of Korean Oriental Medicine 2011;32(6)
  11. Chun WJ, Yoon BG, Kim NI, Lee G, Yang CH, Lee CW, et al. A clinical study of patients with acute liver injury caused by herbal medication in Gyeongju area. Korean J Med. 2002; 63(2): 141-50.
  12. Ghabril M, Chalasani N, Björnsson E. Druginduced liver injury: a clinical update. Curr Opin Gastroenterol. 2010; 26(3):222-6. https://doi.org/10.1097/MOG.0b013e3283383c7c
  13. Arundel C, Lewis JH. Drug-induced liver disease in 2006. Curr Opin Gastroenterol. 2007; 23(3): 244-54. https://doi.org/10.1097/MOG.0b013e3280b17dfb
  14. Arundel C, Lewis JH. Drug-induced liver disease in 2006. Curr Opin Gastroenterol. 2007; 23(3): 244-54.
  15. Rochon J, Protiva P, Seeff LB, Fontana RJ, Liangpunsakul S, Watkins PB, et al. Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury. Hepatology. 2008; 48:1175-83. https://doi.org/10.1002/hep.22442
  16. Rowden AK, Norvell J, Eldridge DL, Kirk MA. Updates on acetaminophen toxicity. Med Clin North Am. 2005; 89(6):1145-59. https://doi.org/10.1016/j.mcna.2005.06.009
  17. Wallace JL. Acetaminophen hepatotoxicity: NO to the rescue. Br J Pharmacol. 2004; 143(1):1-2. https://doi.org/10.1038/sj.bjp.0705781
  18. Wallace JL. Acetaminophen hepatotoxicity: NO to the rescue. Br J Pharmacol. 2004; 143(1):1-2. https://doi.org/10.1038/sj.bjp.0705781
  19. Bussières JF, Habra M. Application of International Consensus Meeting Criteria for classifying drug-induced liver disorders. Ann Pharmacother. 1995; 29(9):875-8.
  20. Alander SW, Dowd MD, Bratton SL, Kearns GL. Pediatric acetaminophen overdose: risk factors associated with hepatocellular injury. Arch Pediatr Adolesc Med. 2000; 154(4):346-50.
  21. Alander SW, Dowd MD, Bratton SL, Kearns GL. Pediatric acetaminophen overdose: risk factors associated with hepatocellular injury. Arch Pediatr Adolesc Med. 2000; 154(4):346-50.
  22. Alander SW, Dowd MD, Bratton SL, Kearns GL. Pediatric acetaminophen overdose: risk factors associated with hepatocellular injury. Arch Pediatr Adolesc Med. 2000; 154(4):346-50.