Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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Clinical characteristics of obese boys and girls in a high school: focused on abdominal fat indices, fatty liver and carotid intima-media thickness

  • Oh, Jung-Eun (Department of Pediatrics, Ewha Womans University School of Medicine) ;
  • Jung, Ji-Young (Department of Pediatrics, Ewha Womans University School of Medicine) ;
  • Kim, Hae-Soon (Department of Pediatrics, Ewha Womans University School of Medicine) ;
  • Hong, Young-Mi (Department of Pediatrics, Ewha Womans University School of Medicine) ;
  • Yoo, Jung-Hyun (Department of Radiology, Ewha Womans University School of Medicine) ;
  • Song, Young-Whan (Department of Pediatrics, Inje University College of Medicine) ;
  • Jung, Jo-Won (Department of Pediatrics, Ajou University School of Medicine) ;
  • Kim, Nam-Su (Department of Pediatrics, Han Yang University College of Medicine) ;
  • Noh, Chung-Il (Department of Pediatrics, Seoul National University College of Medicine)
  • 투고 : 2010.10.16
  • 심사 : 2011.05.13
  • 발행 : 2011.07.15
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초록

Purpose: Our study aimed to evaluated sex differences in clinical features of obese high school students. Methods: One hundred three obese high school students (body mass index [BMI]${\geq}$85th percentile) and 51 control students (BMI<85th percentile) were enrolled in this study. Anthropometric measurements were performed. Fasting serum glucose, insulin, aspartate aminotransferase, alanine aminotransferase, total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and high-sensitive C-reactive protein were measured. Abdominal fat thickness, degree of fatty liver, and carotid intima-media thickness were measured by ultrasound. Results: In control and obese groups, waist circumference was significantly longer in boys but body fat mass was Significantly higher in girls. In the control group, total cholesterol and LDL-C were higher in girls. In the obese group, however, aspartate aminotransferase, alanine aminotransferase and triglyceride were higher and HDL-C was lower in boys. Preperitoneal fat thickness was significantly higher in obese girls. In obese group, the degree of fatty liver was significantly higher in boys. Carotid intima-media thickness was not significantly different between boys and girls. Conclusion: Obese adolescents had distinguishable sex differences in body measurements, metabolic abnormalities, abdominal fat thickness and fatty liver. We can infer that these characteristics may extend into adult obesity.

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참고문헌

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