The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

A Septic Abortion Caused by Campylobacter jejuni bacteremia

Campylobacter jejuni 감염으로 인한 패혈 유산 1예

  • Na, Shin (Department of 1Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Na, Hee-Kyong (Department of 1Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Park, Hyun-Jung (Department of 1Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Park, Young-Hoon (Department of 1Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Whang, Keum-Rock (Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Park, Ki-Ho (Department of 1Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Woo, Jun-Hee (Department of 1Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine)
  • 나신 (울산대학교 의과대학 서울아산병원 감염내과) ;
  • 나희경 (울산대학교 의과대학 서울아산병원 감염내과) ;
  • 박현정 (울산대학교 의과대학 서울아산병원 감염내과) ;
  • 박영훈 (울산대학교 의과대학 서울아산병원 감염내과) ;
  • 황금록 (울산대학교 의과대학 서울아산병원 진단검사의학과) ;
  • 박기호 (울산대학교 의과대학 서울아산병원 감염내과) ;
  • 우준희 (울산대학교 의과대학 서울아산병원 감염내과)
  • Published : 2011.09.01
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Abstract

Campylobacter jejuni was isolated from the blood of a 31-year-old woman who suffered a mid-trimester septic abortion with fever and headache. Histologically, evidence of septic abortion was found, with an intervillous abscess and acute villitis. Complete clinical recovery followed termination of the pregnancy and the use of antibiotics. C. jejuni is an unusual cause of septic abortion in humans. To our knowledge, no case has been reported in Korea.

31세 초임부가 발열과 두통으로 내원하여 임신 중삼분기의 패혈 유산을 진단받았고 혈액배양 검사에서 C. jejuni가 동정되었다. 태반의 병리 소견에서 융모 사이 농양과 함께 급성 융모염이 관찰되었으며 태아 임신 중절과 항생제 사용으로 임상증상이 호전되었다. C. jejuni는 사람에서 발생하는 패혈 유산의 드문 원인균이고 아직까지 우리나라에서 보고된 예가 없어 문헌고찰과 함께 보고하는 바이다.

Keywords

References

  1. Smibert RM. Genus Campylobacter. In: Krieg NR, Holt JG, eds. Bergey's Manual of Systematic Bacteriology. Baltimore: Williams & Wilkins, 1984.
  2. Vinzent R, Dumas J, Picard N. Septicemie grave au cours de la grossesse, due a un vibrion: avortement consecutif. Bull Acad Natl Med (Paris) 1947;131:90-93.
  3. Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 7th ed. New York: Churchill Livingstone, 2010.
  4. Allos BM. Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis 2001;32:1201-1206. https://doi.org/10.1086/319760
  5. Pacanowski J, Lalande V, Lacombe K, et al. Campylobacter bacteremia: clinical features and factors associated with fatal outcome. Clin Infect Dis 2008;47:790-796. https://doi.org/10.1086/591530
  6. Simor AE, Karmali MA, Jadavji T, Roscoe M. Abortion and perinatal sepsis associated with campylobacter infection. Rev Infect Dis 1986;8:397-402. https://doi.org/10.1093/clinids/8.3.397
  7. Simor AE, Ferro S. Campylobacter jejuni infection occurring during pregnancy. Eur J Clin Microbiol Infect Dis 1990;9:142-144. https://doi.org/10.1007/BF01963642
  8. Smith T. The etiological relation of spirilla (Vibrio Fetus) to Bovine abortion. J Exp Med 1919;30:313-323. https://doi.org/10.1084/jem.30.4.313
  9. Gilbert GL, Davoren RA, Cole ME, Radford NJ. Midtrimester abortion associated with septicaemia caused by Campylobacter jejuni. Med J Aust 1981;1:585-586.
  10. Blaser MJ, Berkowitz ID, LaForce FM, Cravens J, Reller LB, Wang WL. Campylobacter enteritis: clinical and epidemiologic features. Ann Intern Med 1979;2:179-185.
  11. Skirrow MB. Campylobacter enteritis: a "new" disease. Br Med J 1977;2:9-11. https://doi.org/10.1136/bmj.2.6078.9
  12. Mertens A, De Smet M. Campylobacter cholecystitis. Lancet 1979;1:1092-1093.
  13. Ezpeleta C, de Ursua PR, Obregon F, Goni F, Cisterna R. Acute pancreatitis associated with Campylobacter jejuni bacteremia. Clin Infect Dis 1992;15:1050. https://doi.org/10.1093/clind/15.6.1050
  14. Blaser MJ, Perez GP, Smith PF, et al. Extraintestinal Campylobacter jejuni and Camphylobacter coli infections: host factors and strain characteristics. J Infect Dis 1986;153:552-559. https://doi.org/10.1093/infdis/153.3.552
  15. Blaser MJ, Reller LB. Campylobacter enteritis. N Engl J Med 1981;305:1444-1452. https://doi.org/10.1056/NEJM198112103052404
  16. Wistrom J, Jertborn M, Ekwall E, et al. Empiric treatment of acute diarrheal disease with norfloxacin: a randomized, Placebocontrolled study: Swedish Study Group. Ann Intern Med 1992;117:202-208. https://doi.org/10.7326/0003-4819-117-3-202
  17. Gaunt PN, Piddock LJ. Ciprofloxacin resistant Campylobacter spp. in humans: an epidemiological and laboratory study. J Antimicrob Chemother 1996;37:747-757. https://doi.org/10.1093/jac/37.4.747