The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Two Cases of Autoimmune Hepatitis Accompanied by Connective Tissue Diseases

자가면역성 간염과 동반된 전신성 홍반성 낭창 및 원발성 쇼그렌 증후군

  • Lee, Gyu-Jin (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Choi, Jung-Min (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Han, Byung-Hoon (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Lee, Sang-Uk (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Yun, Byung-Cheol (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Kim, Geun-Tae (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Hur, Bang (Department of Pathology, Kosin University College of Medicine)
  • 이규진 (고신대학교 의과대학 내과학교실) ;
  • 최정민 (고신대학교 의과대학 내과학교실) ;
  • 한병훈 (고신대학교 의과대학 내과학교실) ;
  • 이상욱 (고신대학교 의과대학 내과학교실) ;
  • 윤병철 (고신대학교 의과대학 내과학교실) ;
  • 김근태 (고신대학교 의과대학 내과학교실) ;
  • 허방 (고신대학교 의과대학 병리과학교실)
  • Published : 2011.06.01
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Abstract

Autoimmune hepatitis is a generally progressive chronic hepatitis of unknown etiology. Systemic lupus erythematosus (SLE) and Sj${\ddot{o}}$gren's syndrome are chronic, multifaceted inflammatory diseases that can affect every organ system, although hepatic involvement is rare. Here, we report two rare cases: autoimmune hepatitis associated with SLE and with primary Sj${\ddot{o}}$gren's syndrome. A 52-year-old woman and a 60-year-old woman were admitted our hospital with jaundice and pruritus. They had no history of viral hepatitis, alcohol consumption, or drug use. The pathological findings, clinical manifestations, and laboratory findings satisfied each of the diagnostic criteria for autoimmune hepatitis as well as for SLE and Sj${\ddot{o}}$gren's syndrome in the first and second cases, respectively. These patients were treated with prednisolone, and then followed regularly.

저자들은 황달 및 가려움증을 호소하는 52세 여자와 60세 여자에서 각각 자가면역성 간염과 동반된 전신성 홍반성 낭창과 원발성 쇼그렌 증후군을 경험하여 문헌고찰과 함께 보고하고자 한다.

Keywords

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