Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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Acute Cerebral Infarction Following Intravenous Glycoprotein IIb/IIIa Inhibitor for Acute Myocardial Infarction

  • Choi, Woong-Gil (Department of Cardiology, Konkuk University School of Medicine, Chungju Hospital) ;
  • Oh, Se-Won (Department of Cardiology, Konkuk University School of Medicine, Chungju Hospital) ;
  • Kim, Young-Joong (Department of Cardiology, Konkuk University School of Medicine, Chungju Hospital) ;
  • Lim, Jong-Gu (Department of Cardiology, Konkuk University School of Medicine, Chungju Hospital) ;
  • Jo, Yoon-Sik (Department of Cardiology, Konkuk University School of Medicine, Chungju Hospital)
  • Published : 2011.09.30
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Abstract

Stroke is a rare but serious complication of acute myocardial infarction (AMI). Currently, glycoprotein (GP) IIb/IIIa inhibitor is used in clinical practice for acute coronary syndromes and percutaneous coronary interventions (PCIs). The incidence of stroke in patients receiving GP IIb/IIIa inhibitor during PCIs is very low. We report the case of a 47-year-old man who presented with AMI and suffered an acute cerebral infarction after infusion of a GP IIb/IIIa inhibitor following primary PCI.

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References

  1. Hess DC, D'Cruz IA, Adams RJ, Nichols FT 3rd. Coronary artery disease, myocardial infarction, and brain embolism. Neurol Clin 1993;11:399-417.
  2. Komrad MS, Coffey CE, Coffey KS, McKinnis R, Massey EW, Califf RM. Myocardial infarction and stroke. Neurology 1984;34:1403-9. https://doi.org/10.1212/WNL.34.11.1403
  3. Akkerhuis KM, Deckers JW, Lincoff AM, et al. Risk of stroke associated with abciximab among patients undergoing percutaneous coronary intervention. JAMA 2001;286:78-82. https://doi.org/10.1001/jama.286.1.78
  4. Mooe T, Olofsson BO, Stegmayr B, Eriksson P. Ischemic stroke: impact of a recent myocardial infarction. Stroke 1999;30:997-1001. https://doi.org/10.1161/01.STR.30.5.997
  5. Behar S, Tanne D, Abinader E, et al. Cerebrovascular accident complicating acute myocardial infarction: incidence, clinical significance and short- and long-term mortality rates. Am J Med 1991;91:45-50. https://doi.org/10.1016/0002-9343(91)90072-6
  6. Torgano G, Zecca B, Monzani V, et al. Effect of intravenous tirofiban and aspirin in reducing short-term and long-term neurologic deficit in patients with ischemic stroke: a double-blind randomized trial. Cerebrovasc Dis 2010;29:275-81. https://doi.org/10.1159/000275503
  7. Oh YJ, Park TH, Choi YJ, et al. Abciximab (ReoPro)-induced thrombocytopenia diagnosed through measurement of heparin-dependent antibody. Korean Circ J 2009;39:75-8. https://doi.org/10.4070/kcj.2009.39.2.75
  8. Frishman WH, Burns B, Atac B, Alturk N, Altajar B, Lerrick K. Novel antiplatelet therapies for treatment of patients with ischemic heart disease: inhibitors of the platelet glycoprotein IIb/IIIa integrin receptor. Am Heart J 1995;130:877-92. https://doi.org/10.1016/0002-8703(95)90091-8
  9. Chang GY. An ischemic stroke during intravenous recombinant tissue plasminogen activator infusion for evolving myocardial infarction. Eur J Neurol 2001;8:267-8. https://doi.org/10.1046/j.1468-1331.2001.00216.x