Serous Cystic Neoplasm: Do We Have to Wait Till It Causes Trouble?

Serous Cystic Neoplasm: Do We Have to Wait Till It Causes Trouble?

  • Hwang, Ho-Kyoung (Department of Surgery, Yonsei University College of Medicine) ;
  • Chung, Young-Eun (Department of Radiology, Yonsei University College of Medicine) ;
  • Kim, Hyun-Ki (Department of Pathology, Yonsei University College of Medicine) ;
  • Park, Jung-Yub (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Choi, Hye-Jin (Department of Medical Oncology, Yonsei University College of Medicine,) ;
  • Kang, Chang-Moo (Department of Surgery, Yonsei University College of Medicine) ;
  • Lee, Woo-Jung (Department of Surgery, Yonsei University College of Medicine)
  • Published : 2011.05.30

Abstract

Serous cystic neoplasm (SCN) of the pancreas is considered a benign tumor with almost no malignant potential. Most surgeons agree that asymptomatic SCN requires only regular observation. However, several complexities and interference with organ preservation during the operation, may develop when a huge symptomatic tumor is treated with surgery. So, the purpose of this study is to develop a potential management plan based on a literature review and by describing three recent cases of SCN of the pancreas. We suggest that SCNs be responded to with a timely and appropriate surgical intervention - before they require clinical attention.

Keywords

References

  1. Becker WF, Welsh RA, Pratt HS. Cystadenoma and cysta denocarcinoma of the pancreas. Ann Surg 1965;161:845-863. https://doi.org/10.1097/00000658-196506000-00005
  2. ReMine SG, Frey D, Rossi RL, Munson JL, Braasch JW. Cystic neoplasms of the pancreas. Arch Surg 1987;122:443-446. https://doi.org/10.1001/archsurg.1987.01400160069010
  3. George DH, Murphy F, Michalski R, Ulmer BG. Serous cystadenocarcinoma of the pancreas: a new entity? Am J Surg Pathol 1989;13:61-66. https://doi.org/10.1097/00000478-198901000-00009
  4. King JC, Ng TT, White SC, Cortina G, Reber HA, Hines OJ. Pancreatic serous cystadenocarcinoma: a case report and review of the literature. J Gastrointest Surg 2009;13:1864-1868. https://doi.org/10.1007/s11605-009-0926-3
  5. Fernandez-del Castillo C, Targarona J, et al. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg 2003;138:427-423. https://doi.org/10.1001/archsurg.138.4.427
  6. Sahani D, Prasad S, Saini S, Mueller P. Cystic pancreatic neoplasms evaluation by CT and magnetic resonance cholangiopancreatography. Gastrointest Endosc Clin N Am 2002;12:657-672. https://doi.org/10.1016/S1052-5157(02)00022-3
  7. Yoon WJ, Lee JK, Lee KH, Ryu JK, Kim YT, Yoon YB. Cystic neoplasms of the exocrine pancreas: an update of a nationwide survey in Korea. Pancreas 2008;37:254-258. https://doi.org/10.1097/MPA.0b013e3181676ba4
  8. Birkmeyer JD, Warshaw AL, Finlayson SR, Grove MR, Tosteson AN. Relationship between hospital volume and late survival after pancreaticoduodenectomy. Surgery 1999;126:178-183. https://doi.org/10.1016/S0039-6060(99)70152-2
  9. Strobel O, Z'graggen K, Schmitz-Winnenthal FH, et al. Risk of malignancy in serous cystic neoplasms of the pancreas. Digestion 2003;68:24-33. https://doi.org/10.1159/000073222
  10. Tseng JF, Warshaw AL, Sahani DV, Lauwers GY, Rattner DW, Fernandez-del Castillo C. Serous cystadenoma of the pancreas: tumor growth rates and recommendations for treatment. Ann Surg 2005;242:413-419.
  11. Balcom JH 4th, Rattner DW, Warshaw AL, Chang Y, Fernandez-del Castillo C. Ten-year experience with 733 pancreatic resections: changing indications, older patients, and decreasing length of hospitalization. Arch Surg 2001;136:391-398. https://doi.org/10.1001/archsurg.136.4.391
  12. Rosok BI, Marangos IP, Kazaryan AM, et al. Single-centre experience of laparoscopic pancreatic surgery. Br J Surg 2010;97:902-909. https://doi.org/10.1002/bjs.7020
  13. Giulianotti PC, Sbrana F, Bianco FM, et al. Robot-assisted laparoscopic pancreatic surgery: single-surgeon experience. Surg Endosc 2010;24:1646-1657. https://doi.org/10.1007/s00464-009-0825-4