The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

A Case of Adult Onset Still's Disease Presented with Acute Febrile Hepatitis

급성 열성 간염 형태로 나타난 성인형 스틸병 1예

  • Lee, Sang-Jun (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Chough, Hong-Sung (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Cho, Min-Keun (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Na, Jee-Sun (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Kim, Hyun-Sook (Department of Internal Medicine, Chosun University College of Medicine) ;
  • Kim, Man-Woo (Department of Internal Medicine, Chosun University College of Medicine)
  • 이상준 (조선대학교 의과대학 내과학교실) ;
  • 조홍성 (조선대학교 의과대학 내과학교실) ;
  • 조민근 (조선대학교 의과대학 내과학교실) ;
  • 나지선 (조선대학교 의과대학 내과학교실) ;
  • 김현숙 (조선대학교 의과대학 내과학교실) ;
  • 김만우 (조선대학교 의과대학 내과학교실)
  • Published : 2011.05.01
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Abstract

Adult-onset Still's Disease (AOSD) is a rare, immune-mediated, multisystem inflammatory disorder characterized by quotidianspiking fevers, an evanescent rash, arthritis, lymphadenopathy, splenomegaly, a sore throat, leukocytosis, and liver dysfunction. Itsclinical manifestations are very diverse, from relatively mild symptoms to severe complications, such as disseminated intravascularcoagulation, cardiac tamponade, acute respiratory distress syndrome, hemophagocytic syndrome, and hepatic failure. Hepatic failureis an extremely rare complication that could lead to death. Therefore, early diagnosis and treatment are important. We report acase of adult-onset Still's disease with acute febrile hepatitis.

AOSD는 다양한 중증도의 임상증상을 보이는 드문 질환으로 급성 간부전이 동반되는 경우는 드물지만 사망률이 높은 만큼 신속한 진단과 적절한 치료가 무엇보다 중요하다. 저자들은 스테로이드로 성공적으로 치료한 급성 열성 간염을 동반한 AOSD 1예를 경험하였기에 보고하는 바이다.

Keywords

References

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