The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

A Case of Undifferentiated Carcinoma with Osteoclast-Like Giant Cells in the Pancreas

췌장의 파골세포양 거대세포 미분화 암종 1예

  • Yang, Suh-Yoon (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Do, Jae-Hyuk (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Oh, In-Soo (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Lee, Hyun-Woong (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Choi, Chang-Hwan (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Chang, Sae-Kyung (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Park, Eon-Sub (Department of Pathology, Chung-Ang University College of Medicine)
  • 양서윤 (중앙대학교 의과대학 내과학교실) ;
  • 도재혁 (중앙대학교 의과대학 내과학교실) ;
  • 오인수 (중앙대학교 의과대학 내과학교실) ;
  • 이현웅 (중앙대학교 의과대학 내과학교실) ;
  • 최창환 (중앙대학교 의과대학 내과학교실) ;
  • 장세경 (중앙대학교 의과대학 내과학교실) ;
  • 박언섭 (중앙대학교 의과대학 병리학교실)
  • Published : 2011.01.01
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Abstract

Undifferentiated carcinomas with osteoclast-like giant cells are rare pancreatic and periampullary neoplasms that mimic giant cell tumors of bone morphologically. Recently, we experienced an osteoclast-like giant cell tumor arising in the tail of the pancreas. A 76-year-old male was admitted with epigastric discomfort and indigestion. Abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI) showed a $3{\times}3-cm$ mass containing necrotic and hemorrhagic areas in the tail of the pancreas. A distal pancreatectomy and splenectomy were performed. Histological examination showed tumor cell components consisting of mononuclear pleomorphic cells admixed with osteoclastic giant cells. The final diagnosis was undifferentiated carcinoma with osteoclast-like giant cells with ductal adenocarcinoma in the pancreas.

저자들은 상복부 불편감과 소화불량을 있는 환자에서 췌장미부에 선암종을 동반한 파골세포양 거대세포 미분화 암종을 진단하였고, 수술적 절제 후 방사선 치료와 항암화학요법을 시행한 예를 경험하였기에 문헌고찰과 함께 보고한다.

Keywords

References

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