Principles and Practice of Diuretic Therapy

이뇨제 사용의 원칙과 실제

  • Jeon, Un-Sil (Division of Nephrology, Department of Internal Medicine, Korea University Guro-Hospital, Korea University College of Medicine)
  • 전은실 (고려대학교 의과대학 구로병원 신장내과)
  • Published : 2011.01.01

Abstract

Diuretic drugs are the most commonly used agents to control edema or volume overload. However, the clinical use of diuretics is not confined to edema control. Recently, diuretics have been revisited for the management of various diseases, including hypertension and congestive heart failure. Diuretics are classified mainly by their sites of action in the renal tubules, and have unique characteristics and adverse effects according to their mechanisms of action. To use diuretics adequately, it is very important to understand their characteristics.

Keywords

References

  1. Antes LM, Fernandez PC. Principles of diuretic therapy. Disease-A-Month 1998;44:254-268. https://doi.org/10.1016/S0011-5029(98)90003-7
  2. Mount DB, Yu ASL. Brenner and Rector's the Kidney. 8th ed. St Louis: WB Saunders, 2007.
  3. Ellison DH, Wilcox CS. Brenner and Rector's the Kidney. 8th ed. St Louis, WB Saunders, 2007.
  4. Bhardwaj A. Osmotherapy in neurocritical care. Curr Neurol Neurosci Rep 2007;7:513-521. https://doi.org/10.1007/s11910-007-0079-2
  5. Brater DC. Diuretic therapy. N Engl J Med 1998;339:387-395. https://doi.org/10.1056/NEJM199808063390607
  6. Shankar SS, Brater DC. Loop diuretics: from the Na-K-2Cl transporter to clinical use. Am J Physiol Renal Physiol 2003;284:F11-F21. https://doi.org/10.1152/ajprenal.00119.2002
  7. Wilcox CS. New insights into diuretic use in patients with chronic renal disease. J Am Soc Nephrol 2002;13:798-805.
  8. Sarafidis PA, Georgianos PI, Lasaridis AN. Diuretics in clinical practice. Part I: mechanisms of action, pharmacological effects and clinical indications of diuretic compounds. Expert Opin Drug Saf 2010;9:243-257. https://doi.org/10.1517/14740330903499240
  9. Ernst ME, Moser M. Use of diuretics in patients with hypertension. N Engl J Med 2009;361:2153-2164. https://doi.org/10.1056/NEJMra0907219
  10. Shah SU, Anjum S, Littler WA. Use of diuretics in cardiovascular diseases: (1) heart failure. Postgrad Med J 2004;80:201-205. https://doi.org/10.1136/pgmj.2003.010835
  11. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). JAMA 2002;288:2981-2997. https://doi.org/10.1001/jama.288.23.2981
  12. Asare K. Management of loop diuretic resistance in the intensive care unit. Am J Health Syst Pharm 2009;66:1635-1640. https://doi.org/10.2146/ajhp090068