The Korean journal of internal medicine

  • 제26권1호
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  • Pages.103-107
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  • 2011
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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Duodenal Somatostatinoma: A Case Report and Review

  • Kim, Jung-A (Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital) ;
  • Choi, Won-Ho (Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital) ;
  • Kim, Chul-Nam (Department of General Surgery, Inje University College of Medicine, Ilsan Paik Hospital) ;
  • Moon, Young-Soo (Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital) ;
  • Chang, Sun-Hee (Department of Pathology, Inje University College of Medicine, Ilsan Paik Hospital) ;
  • Lee, Hye-Ran (Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital)
  • 발행 : 2011.03.01
⟨ 이전 논문 다음 논문 ⟩

초록

Somatostatinomas are rare functioning carcinoid tumors that usually arise in the pancreas and duodenum. They are seldom associated with typical clinical symptoms; their diagnosis is confirmed only by histological and immunohistochemical studies and the presence of specific hormones. Two distinct clinicopathological forms of somatostatinoma exist: duodenal and pancreatic somatostatinomas. Clinically, compared to pancreatic somatostatinomas, duodenal somatostatinomas are more often associated with nonspecific symptoms and neurofibromatosis, but less often with somatostatinoma syndrome or metastasis. Histologically, duodenal somatostatinomas frequently have psammoma bodies in the tumor cells. We report a case of duodenal somatostatinoma in 58-year-old man with vague epigastric pain and nausea. He did not have diabetes, steatorrhea, or cholelithiasis. Abdominal computed tomography showed a 25-mm mass in the duodenum and 25-mm nodule in the liver. Endoscopic retrograde cholangiopancreatography showed a duodenal submucosal tumor. Although the endoscopic biopsies were free of malignancy, the patient subsequently underwent Whipple's operation for the duodenal mass. Examination revealed as a somatostatinoma using a special stain for somatostatin.

키워드

참고문헌

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피인용 문헌

  1. A Case of a Pancreatic Tumor Producing Somatostatin with Liver Metastasis Two and 22 Years after Initial Resection vol.46, pp.5, 2011, https://doi.org/10.5833/jjgs.2012.0216
  2. Gastric Somatostatinoma: An Extremely Rare Cause of Upper Gastrointestinal Bleeding vol.46, pp.5, 2013, https://doi.org/10.5946/ce.2013.46.5.582
  3. Somatostatinoma of the Ampulla: An Incidental Postoperative Finding Following Colorectal Cancer Resection vol.3, pp.2, 2011, https://doi.org/10.14309/crj.2016.16
  4. Duodenal somatostatinoma presenting as obstructive jaundice with the coexistence of a gastrointestinal stromal tumour in neurofibromatosis type 1: a case with review of the literature vol.12, pp.1, 2011, https://doi.org/10.1136/bcr-2018-226702
  5. Phase I Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines Emulsified in Montanide ISA 720VG and Nor-MDP Adjuvant in Patients with Advanced Solid Tumors vol.25, pp.12, 2011, https://doi.org/10.1158/1078-0432.ccr-18-3997
  6. Gastrointestinal neuroendocrine tumors in 2020 vol.12, pp.8, 2011, https://doi.org/10.4251/wjgo.v12.i8.791
  7. Somatostatinoma and Neurofibromatosis Type 1-A Case Report and Review of the Literature vol.10, pp.9, 2011, https://doi.org/10.3390/diagnostics10090620
  8. Somatostatin and Its Receptor System in Colorectal Cancer vol.9, pp.11, 2011, https://doi.org/10.3390/biomedicines9111743