대한영상의학회지 (Journal of the Korean Society of Radiology)

  • 제65권5호
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  • Pages.461-464
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  • 2011
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  • 1738-2637(pISSN)
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  • 2288-2928(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지

광범위한 침범을 보였던 급성 Marchiafava-Bignami 병의 Magnetic Resonance 소견: 1 증례

Magnetic Resonance Finding of Acute Marchiafava-Bignami Disease with Diffuse Involvement: A Case Report

  • 허영진 (인제대학교 의과대학 부산백병원 영상의학과학교실) ;
  • 정해웅 (인제대학교 의과대학 부산백병원 영상의학과학교실) ;
  • 인현신 (인제대학교 의과대학 부산백병원 영상의학과학교실)
  • Heo, Young-Jin (Department of Radiology, Busan Paik Hospital, Inje University School of Medicine) ;
  • Jeong, Hae-Woong (Department of Radiology, Busan Paik Hospital, Inje University School of Medicine) ;
  • In, Hyun-Sin (Department of Radiology, Busan Paik Hospital, Inje University School of Medicine)
  • 발행 : 2011.11.01
⟨ 이전 논문 다음 논문 ⟩

초록

Marchiafava-Bignami 병은 만성 알코올 중독과 관련성이 많은 드문 독성 장애이다. 이는 뇌들보의 점차적인 탈수초화와 괴사를 나타낸다. 진행과정 중에 인접한 백색실과 피질하의 병변까지 확산될 수 있다. 우리는 액체감쇠역전회복영상과 확산강조영상에서 뇌들보, 백질, 겉질 척수로, 속섬유막, 양측 소뇌다리 등에 광범위하게 대칭적으로 고신호강도를 보였던 1증례를 경험하여 보고하고자 한다.

Marchiafava-Bignami disease (MBD) is a rare toxic disorder strongly associated with chronic alcoholism (1-3, 6, 7). It is characterized by progressive demyelination and necrosis of the corpus callosum. The process may extend to neighboring white matter and subcortical regions. We report a case of MBD in which fluid-attenuated inversion recovery and diffusion-weighted imaging revealed symmetrical hyperintense lesions with diffuse involvement of the corpus callosum, white matter, corticospinal tract, internal capsule, and middle cerebellar peduncle (3, 4, 8).

키워드

참고문헌

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  2. Arbelaez A, Pajon A, Castillo M. Acute Marchiafava-Bignami disease: MR findings in two patients. AJNR Am J Neuroradiol 2003;24:1955-1957
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  5. Tuntiyatorn L, Laothamatas J. Acute Marchiafava-Bignami disease with callosal, cortical, and white matter involvement. Emerg Radiol 2008;15:137-140 https://doi.org/10.1007/s10140-007-0640-y
  6. Ihn YK, Hwang SS, Park YH. Acute Marchiafava-Bignami disease: diffusion-weighted MRI in cortical and callosal involvement. Yonsei Med J 2007;48:321-324 https://doi.org/10.3349/ymj.2007.48.2.321
  7. Yoshizaki T, Hashimoto T, Fujimoto K, Oguchi K. Evolution of Callosal and Cortical Lesions on MRI in Marchiafava-Bignami Disease. Case Rep Neurol 2010;2:19-23 https://doi.org/10.1159/000296705
  8. Shin HE, Kim JG, Jo SR, Jeong SH, Yoon SJ. Acute Marchiafava-Bignami disease with typical white matter involvement on diffusion weighted MRI. J Korean Neurol Assoc 2008;26:376-378
  9. Jang HW. Cortical involvement of Marchiafava-Bignami disease: a case report. J Korean Radiol Soc 2007;56:217-219 https://doi.org/10.3348/jkrs.2007.56.3.217