Neonatal Medicine

The Korean Society of Neonatology (대한신생아학회)
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Two Cases of Dry Lung Syndrome

Dry lung syndrome 2예

  • Song, In-Gu (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Su-Yeong (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Lee, Ju-Young (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Lee, Eun-Hee (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Sohn, Jin-A (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Choi, Eun-Jin (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Eun-Sun (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Lee, Hyun-Ju (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Lee, Jin-A (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Choi, Chang-Won (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Ee-Kyung (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Han-Suk (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Byeong-Il (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Choi, Jung-Hwan (Department of Pediatrics, Seoul National University College of Medicine)
  • 송인규 (서울대학교 의과대학 소아과학교실) ;
  • 김수영 (서울대학교 의과대학 소아과학교실) ;
  • 이주영 (서울대학교 의과대학 소아과학교실) ;
  • 이은희 (서울대학교 의과대학 소아과학교실) ;
  • 손진아 (서울대학교 의과대학 소아과학교실) ;
  • 최은진 (서울대학교 의과대학 소아과학교실) ;
  • 김은선 (서울대학교 의과대학 소아과학교실) ;
  • 이현주 (서울대학교 의과대학 소아과학교실) ;
  • 이진아 (서울대학교 의과대학 소아과학교실) ;
  • 최창원 (서울대학교 의과대학 소아과학교실) ;
  • 김이경 (서울대학교 의과대학 소아과학교실) ;
  • 김한석 (서울대학교 의과대학 소아과학교실) ;
  • 김병일 (서울대학교 의과대학 소아과학교실) ;
  • 최중환 (서울대학교 의과대학 소아과학교실)
  • Published : 2011.05.31
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Abstract

Preterm infants with oligohydramnios after preterm premature rupture of membranes can present with severe respiratory distress immediately after birth, and the most common cause is pulmonary hypoplasia. Unlike infants with pulmonary hypoplasia, some cases have shown dramatic improvement with aggressive ventilatory support during the initial 1-2 days of distress: those patients have been defined as having dry lung syndrome. It is assumed that oligohydramnios leads to functional pulmonary hypoplasia by compression of the fetal lungs: some of the improvement in dry lung syndrome may thus have resulted from inflation of compressed lung tissue and increase of lung compliance. We report two incidences of dry lung syndrome that were treated successfully with high inflation pressure and inhaled nitric oxide (NO): these are the first dry lung syndrome cases to be reported in Korean infants.

조기 양막 파수에 의한 양수 과소증 산모에게서 출생한 미숙아들에게 발생하는 호흡 곤란의 원인으로 폐 저형성증이나 폐고혈압증, RDS, 폐렴 등을 들 수 있다. 이들과 유사한 초기 경과를 보이는 DLS는 이들에 비해 빠른 회복을 보이고 적은 후유증을 남기는 특징을 가져 다른 질환군으로 분류할 수 있다. 본 연구에서는 양수 과소증 산모에게서 출생한 미숙아로 출생 초기심한 호흡 곤란을 보였지만 X-ray 소견이 RDS에 합당하지 않거나 폐 표면 활성제에 반응하지 않았으나 높은 흡기 압력과 NO가스로 치료 후 급속도로 호전되어 DLS로 진단된 2예를 보고하였다. 호흡 곤란을 보이는 미숙아의 치료 시 다른 질환들이 감별되는 경우 DLS를 염두하여 높은 흡기 압력으로 인공 호흡기치료를 하고 심초음파 검사 등을 시행 후 NO 가스의 사용을 적극 고려해야 한다.

Keywords

References

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