Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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Cytomegalovirus Infectious Mononucleosis in a Patient with a Gastric Ulcer

건강한 성인에서 발생한 거대세포바이러스 전염단핵구증과 동반된 위궤양

  • Park, Se-Yoon (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Lee, Eun-Jung (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Lee, Tae-Hee (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Koo, So-My (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Kim, Jin-Nyoung (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Jeon, Min-Huok (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Choo, Eun-Ju (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Kim, Tae-Hyong (Department of Internal Medicine, Soonchunhyang University College of Medicine)
  • 박세윤 (순천향대학교 의과대학 내과학교실) ;
  • 이은정 (순천향대학교 의과대학 내과학교실) ;
  • 이태희 (순천향대학교 의과대학 내과학교실) ;
  • 구소미 (순천향대학교 의과대학 내과학교실) ;
  • 김진녕 (순천향대학교 의과대학 내과학교실) ;
  • 전민혁 (순천향대학교 의과대학 내과학교실) ;
  • 추은주 (순천향대학교 의과대학 내과학교실) ;
  • 김태형 (순천향대학교 의과대학 내과학교실)
  • Published : 2011.06.30
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Abstract

Cytomegalovirus (CMV) is a prevalent pathogen, with 98~100% of Korean adults showing prior exposure by serology. A primary infection, such as CMV infectious mononucleosis, is very rare. CMV infectious mononucleosis often presents an initial diagnostic problem. Patients are often hospitalized with a wide variety of clinical diagnoses including fever of unknown origin without pharyngitis and lymphadenopathy. CMV gastrointestinal infections are rare in previously immunocompetent individuals. The most common sites involved are the colon and rectum, although lesions of the stomach have also been described. It is unusual to see CMV infectious mononucleosis and CMV gastrointestinal infection in the same patient. Our patient received symptomatic treatment and fully recovered. We present a case of CMV infectious mononucleosis with gastric ulcers in a previously healthy adult.

우리나라 성인의 CMV 항체 양성률은 98~100%로 높아 일차감염 형태인 CMV 전염단핵구증은 매우 드물다. CMV 전염 단핵구증은 임상 증상이 젼형적이지 않아 의심하기 어렵고 인 두염과 림프절병증 없이 열이 지속될 수 있어 불명열의 감별진단이 된다. 한편 CMV에 의한 침습적인 감염은 정상 면역 성인에서는 드물며 위장관을 침범할 경우 주로 대장과 직장을 침범하여 위 침범은 매우 드물다. 저자들은 지속된 고열을 주소로 내원한 정상 면역 성인에서 CMV 전염단핵구증과 동반된 CMV 위궤양을 진단하고 항바이러스제 없이 좋아진 1예를 경험하여 국내 문헌 고찰과 함께 보고한다.

Keywords

References

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